Bisphosphonates - he aha te mea te reira? Bisphosphonates mō te osteoporosis

pūnaha musculoskeletal mahi tetahi o nga mahi matua i roto i te tinana tangata. Ko reira ko te tautoko mo nga tinana katoa. Bone hauora whai wāhi nui. A, no te reira e raruraru i roto i nga hononga, tuarā, piere auau puta, Kei te tino heke te kounga o te tangata o te ora. Ko tētahi taua mate e maha i tahi e taua tohu he osteoporosis.

Ki te i roto i te wa ki te kite i te tākuta, he reira taea ki te tino whakapai ake i te huru o te manawanui. I tēnei wā, e whakamahia ana bisphosphonates ki te hamani osteoporosis. Ka taea e ēnei taero hoatu tumanako o te rongoa. Kia kite a he aha te ahua o taero.

He aha e bisphosphonates

Ko tōna ingoa, kua riro tenei rōpū o taero no te mea o te ihirangi i te hanganga o te rua phosphonates. Ko whai hua te tikanga o te mahi no te mea o te ritenga nui ki pirofosfonatami e whai he pānga nui i runga i te ture o te ihirangi konupūmā i roto i te wheua.

Ki te hanganga rite, bisphosphonates tautāwhi i whākōkī e taea te tikanga o te pirofosfonaty. mea ratou ki te here katote konupūmā me te utu hoki ki te wheua a ratou.

Ko te taha ki pai o te fariiraa o enei taero ko e te raau taero e roto i bisphosphonates, whai noa i te pānga whiriwhiri i runga i te pūnaha kōhiwi, te wahi i te haaputuputuraa o te konupūmā.

No te mea o tenei mahi i roto i te maimoatanga o te osteoporosis ko reira taea ki te ārai i te mate o te konupūmā me te ūkuikui, e kua he pānga pai i runga i te maimoatanga.

momo o bisphosphonates

E rave rahi tonu e kore e mohio e pā ana ki bisphosphonates. He aha te mea te reira? Kei te whakawhanakehia te reira i teie nei te toru o nga whakatupuranga o tenei rōpū o taero. tonu Doctors ki te whakamahi i taero, me nga whakatupuranga tuatahi e rua. Na ere i roto maha taero bisphosphonates, e taea te wehea katoa o ratou ki ngā rōpū matua e rua:

1. Simple kore kei roto hauota.
2. Ko te rōpū o bisphosphonates, e ngā hauota - aminobisphosphonates.
   

Ko te rerekētanga i waenganui i te rōpū e rua takoto i roto i te meka e whai ratou pānga rerekē i runga i osteoclasts.

bisphosphonates hauota-kei roto

He aha te mea te reira? Enei moni i roto i tona hanganga kei te kai e whai ake nei:

1. waikawa Ibandronatovaya no ki te toru o nga whakatupuranga, synthesized tata kua whakamahia rawa pai mo te ārai o te osteoporosis i roto i nga wahine, ngā menopausal.
2. waikawa Zolendronovaya tīpakongia mahi i runga i te kiko wheua, kua he pānga anti-puku korerotia. I runga i te pūtake o tenei taonga hua taero pērā i "Zometa", "Zolendronat".
3. correctors konutai Alendronate pā ana ki te pākia e kore-hormonal i roto i te wheua kikokiko, whakatairanga hanganga tika o te hanganga wheua.
4. konutai Ibandronate i runga e hua "Bonviva", "Boniva", "Bondronat" inhibits mahi osteoclast, engari e kore e pā ratou tau. He whai hua ēnei bisphosphonates mō te maimoatanga o te osteoporosis, rawa rite te kaihoko prophylactic i roto i nga wahine menopausal.
   

Kia mōhio e kia kore whaiaro medicate-, me kia whakaritea koe rongoā i te tākuta.

bisphosphonates ohie

E kore kei roto taero bisphosphonate hauota mō te osteoporosis e hoki mātātoa whakamahia. Ko ētahi o ēnei:

1. "Etidronate" i roto i te puka o papa me werohanga. Kei te maha i te reira whakaritea osteoporosis kore anake, engari ano mo te mate o Paget, hypercalcemia, e puta i runga i te whakamārama o te mate pukupuku.
2. tukuna "Clodronate" kei roto i te puka o capsules, papa me rongoā. osteoporosis tōtika me te osteolysis.
3. "Tiludronate" te tikanga whakaritea anake hoki ngā pakeke e mamae i te mate o Paget. Tamariki, kua contraindicated reira.
   

Kei te whakapono te reira e whai enei rōpū e rua o taero pānga rerekē i runga i te toa, me te tinana wahine, na kotiro ataahua, he rongoa hauota-kei roto pai hāngai. I roto i tetahi take, ko te whiriwhiri ko te ki te mahi anake to koutou tākuta.

Miramira i roto i tini o nga mate

He he he rārangi katoa o mate mo e taea whai bisphosphonate therapy te pānga pai.

1. Osteoporosis.
2. Myeloma.
3. Deforming osteodystrophy.
4. hyperparathyroidism Paraimere.
5. Tūkinotanga o te tukanga o te wheua hanganga.
6. A, no te wheua metastases.

Ia o enei tikanga anake whakatakoto te tākuta he tarukino, tona inenga me te roanga o te whakamahi. Whai wāhi i roto i te whaiaro maimoatanga-, ka taea e kino anake te tinana.

tikanga o te mahi

Mai i bisphosphonates mō taero osteoporosis ko te whakamahia tino whānui, he mea e tika ana ki te nau fakamahino'i e te huarahi o to ratou mahi.

E whakahoutia te pūtau katoa i roto i to tatou tinana wā, ka taea te taua kia mea e pā ana ki te wheua. Kei te tonu te reira e te toenga o osteoblasts, e he kawenga mō te kōtuitui o kiko hou, a ka he kawenga mo tona whakangaromanga osteoclasts. Na, BF hopoia maere haukoti i te mahi o osteoclasts, a i roto i ētahi wā noa tīmata tikanga o te whakangaromanga-whaiaro.

Kei te mea te reira e i te wa nei, kua i taea ki te tino feruri i roto i pehea ki te whakahaere i bisphosphonates poraka wheua whakangaromanga pūtaiao. Kei te anake mohiotia te reira e kia kia honoa enei taero ki hydroxyapatite i roto i te wahi wheua, reira te huri i te wheua piko.

Ka taea hoki te mōhio e ki te whakamahia hoki te wa roa, e mo te mate pukupuku therapy i runga i enei bisphosphonates āhua tata whakamahia ki te hamani osteoporosis.

metastases Bisphosphonates

Ki te whanaketanga o te mate pukupuku mai i te wā ka pakaru i atu pūtau mate pukupuku i te puku tuatahi me ona horapa puta noa i te tinana. I te wahi hou e piri ratou, ka timata ki te tupu, hanga metastases.

Ko te kiko wheua Kei te whakahoutia tonu, na faarahi te reira i te tūponotanga o te mate i te hematogenous. A, no te whiwhi ngā pūtau mate pukupuku ki te hinu wheua wheua, whakapōrearea e ratou te interplay noa i waenganui i osteoclasts me osteoblasts, e tika ana ki te whanaketanga rerekē o te wheua kiko.

Mai te whakatau i te aroaro o te metastasis he uaua, no te mea i roto i te tīmatanga o nga wāhanga, puta ngā tenei tukanga kahore tohu, ki te mate pukupuku me haere i te hi'opo'a maitai ki te tāutu i aronga tuarua.

I roto i maimoatanga katoa metastases e whakamahia whānuitia Bisphosphonates. E tino ngāwari ēnei taero nohotahi e tūroro, ratou uaua i ngā pānga taha.

Ka taea te ngā ratou ki iraruke me te hahau. i tāutuhia, no te te whakamahi i taua raau taero whakaiti i roto i te pā o te wheua metastasis i mate pukupuku uma, me myeloma maha.

A, no te whakawhanake hypercalcemia i te mea tata noa i mate oncological, taero i te pānga nui i roto i te puka o werohanga me infusions. Kua whakaaturia ngā hua pai taua tikanga rite "waikawa Zolendronovaya", "Pamidronate". Kua he torutoru ra i muri i tomokanga o whakamātautau maimoatanga whakaatu konupūmā toto Whakapūnoa, a taea te pānga tonu hoki ki runga ki te maha nga ra.

tūtohutanga motuhake mō te fariiraa i bisphosphonates

Ki te kahore i koe i rongo e pā ana ki bisphosphonates, he aha te mea te reira, korero te tākuta. kia kawea Whakaae o enei taero i rite ki etahi tikanga:

• Me tango e koe rongoā i muri i oho, i te iti rawa kia kotahi haora i mua i te kai.
• Horoia iho ki te nui o te wai kia.
• Kaua e whakamahi i zapivaniya atu wai, pērā i te wai, tea, te taofe. ārai ratou te absorption o bisphosphonates.
• I muri i te whakamahi o te papa e kore e taea takoto iho, e pā ana ki te hawhe haora i roto i te tūranga tika ki te whai i iti te pū kai.
• E kore e tūtohu ana ki te whakakotahi i te BF fariiraa ki konupūmā supplementation, konupora, rino, me te konumohe.

Ki te whai koe i katoa o enei tūtohutanga, e kore te bisphosphonate e kawea pānga taha e hiahiatia.

Bisphosphonates mō te osteoporosis: pai me ngā raruraru

I roto i te maimoatanga o bisphosphonates nuitia whakamahia mō te osteoporosis. E whakamahia ōrite pai te taero mo e rua nga tangata me nga wahine. kia ngā te painga matua o enei raau taero:

• e kore e roto i te reira i hormones.
• Kaua e whai wāhi ki te whanaketanga o mate Cardiovascular.
• puku mārere whakamahi BF kore ahunga whakamua.

Otiia i roto i tetahi hinu, ko te wa katoa e taea ki te kitea he rere i roto i te hinu. Bisphosphonates, ahakoa to ratou miramira i te maimoatanga o te osteoporosis, he tawhiti tonu i tino. entrainment nui o fariiraa e taea te hoatu i te pānga taha e whai ake nei:

• Pēhia ngā te ate, me nga whatukuhu.
• Ki te whakahaerea e pâmuhia, he reira pea ki te whakawhanake hypocalcaemia.
• pea te reira i te whewhe pū kai puku ranei.
• He rashes i runga i te tinana.
• I roto i te tahi mau i reira ko te whānui ngoikore, ahuatanga, me te whakapairuaki.
• Mamae i roto i te uaua.
• raruraru Vision.
• Korere korere ranei.
  

E kore e taea e tatou te mea e me whakaatu katoa o enei pānga houhou iho i roto i nga manawanui, engari e hiahia ana koe ki te mohio e pā ana ki a ratou. Ki te ko koe bisphosphonates whakaritea, he aha te mea reira, te whakamārama ki te tākuta, ka whiriwhiri ia te inenga tarukino taua, me te roanga o te maimoatanga.

He whai hua i roto i te maimoatanga o te osteoporosis me ētahi atu mate pērā taero. I mua i te tautapa koe he rongoā, e hiahiatia ana te tākuta kei te ki te kawe i roto i te rangahau ki te kitea i roto i te āhua o te pākia i roto i te wheua, me te konupūmā homeostasis, na e kore e whakaaro koe ki te whakahau taero i roto i tenei rōpū.

, Me koe ki te arahi i te āhua noho hauora, te whai i ngā taunakitanga katoa o tākuta, kai tika ki te karo ia ki te huihui ki rongoā. Anake i roto i tenei take, to koutou pūnaha kōhiwi e pai.