Tohutohu mō te whakamahi, urupare me te tairitenga "Ketanova"

He aha whakarite he tairitenga "Ketanova" ka mea te tarukino iho? Tenei ka ako koe i nga rauemi o te tuhinga. whakamōhio hoki matou ki a koutou ki te tohutohu mō te whakamahi o te rongoā, hoatu pārongo i runga i te puka tuku, tauhohe kino, hanganga, contraindications, utu, me te pera i runga i.

Composition, tākai, puka tuku

Orotahi "Ketanova" ka kanohi e te taputapu ano kia whai ahua tino rerekē o te tuku. tei te ohipa i runga i te āhua o te mamae, te wahi o to ratou wāhi me te huru o te manawanui.

I tēnei wā, tarukino "Ketanov" he wātea i roto i te puka e rua rerekē. whakaaro tatou ia o enei i roto i te kōrero atu.

• papa Film-pani. Ko te wāhanga kaha o te tarukino he ketorolac tromethamine. Ko te wāhanga pŭpŭ tauturu, na ngā ratou witi māngaro, stearate konupora, microcrystalline cellulose me te hauhā silicon colloidal. Ko te hanganga o te paninga kiriata ngā papa hydroxypropylmethylcellulose, wai e purea ana, polyethylene glycol, Titanium hāorarua me talc pure. Me kï reira e kei taua tairitenga "Ketanova" rite "Ketorolac", te taonga kaha taua. faaineineraa i Tirohia hokohoko i roto i opupu konumohe, e kua whakanohoia i roto i te puranga o te pepa. kia kia kotahi mōkihi i tekau ki te kotahi rau papa.

• Werohanga "Ketanov". Werohanga, analogues o nei e whakaaturia ana i raro nei, i roto i ano hoki tenei whakauru kaha rite ketorolac tromethamine. I tua atu, ngā te otinga i roto i tona hanganga, me wāhanga pŭpŭ tauturu i roto i te puka o te konutai pūhaumāota, wai hoki i werohia, disodium edetate, te waihā me te konutai waihā. Rongoā e hokona i roto i te oko o te kotahi ritamano. pea te kātene rima tekau ranei oko.

Ko te āhuatanga pharmacodynamic o te analgesic

He aha ngā āhuatanga pharmacodynamic e whakaaro he tarukino me tona ōrite? "Ketanov" (papa me werohanga) he pānga analgesic korerotia. He āhuatanga antipyretic me anti-inflammatory āhua i te tarukino.

E ai ki nga tohunga, te parau tumu o te mahi o te tarukino e pā ana ki inhibition (kore-whiriwhiri) mahi o te paru Cox-2 me Cox-1. puta tenei tukanga i roto i te kopa piringa. Taua te rongo ai inhibition o PG biosynthesis, modulators arā thermoregulation, mamae tūtohutanga me te mumura.

papa Taupānga "Ketanov" whakahaere intramuscular o te otinga ranei whakatairanga hanganga o te ranunga racemic [-] S- a [+] R-poinanaha. Ratau, te pānga analgesic o te tarukino he tika ki anake [-] S-āhua.

Me kï reira e kore e te tarukino tautāwhi respiration, e kore pānga i runga i te mau farii ohipa opioid, e kore e riro te reira pānga anxiolytic me whakarokiroki, me e kore e meinga fakafalala.

He aha e hiahia ana koe ki te mohio i mua i te tango i tenei hua tona ōrite ranei? "Ketanov" (pire me werohanga) i runga i te kaha o tona pānga analgesic he rite anake ki taua o rehunanu. E ai ki te tohunga, tenei te tikanga tino pai ki te katoa atu taero kore-steroidal.

I muri i te pānga whakahaere analgesic-waha intramuscular ranei kitea i roto i te haora, me te hawhe, aua. tutuki te pānga mōrahi o te tarukino te i roto i 60-120 meneti.

āhuatanga pharmacokinetic

Te raau taketake, me te tetahi orotahi "Ketanova" i muri i ingestion kaua pai whenumi i roto i te wahi gastrointestinal. tae te kukū rawa o tarukino i roto i te toto e muri e pā ana ki e wha tekau meneti i muri i ingestion nohopuku papa (10 mg). Me kï reira e te kohi o te kai hinuhinu me paraurehe taea te whakaiti i te kukū mōrahi o te raau taero i roto i te toto me te pupuri tona paetae i te ono tekau meneti.

Mō 99 ōrau o te moni herea te ki pūmua wē. A, no te te maha o ngā matū hypoalbuminemia noa i roto i nga piki toto. Ki te whakaaro ki te bioavailability o te tarukino, he reira e pā ana ki 80-100%.

Ki te te tere me te tino whenumi whakahaere intramuscular ki te tarukino toto "Ketanov". Analogs (Kua Ukraine kua whakaputa anake "Ketorolac") rite te pai whenumi.

I muri i werohia intramuscular o 30 mg o te tarukino ko ona teitei micrograms kukū 1,75-3,2 / ml, me te whakamahi i 60 mg - 3,25-5,75 g / ml. kitea te kukū mōrahi o tarukino i roto i te toto i roto i 15-20 me 35-65 meneti, aua.

Ahakoa te ô i tarukino ki te waiu, uma? A utu, a cheap orotahi "Ketanova", me ia whakaaro taea ngāwari te tarukino tomo ki roto ki te waiu, uma. puta tonu tenei i muri i te horopeta tuatahi o te medicament i roto i te nui o 10 milligrams. tae te kukū rawa o tarukino i roto i te waiu i te inenga e muri e pā ana ki 120 meneti, me te he 7.3 ng / l.

metabolized Mō 50% o te horopeta e whakahaeretia o te raau taero i roto i te ate. Ka rite ki te hua, e hanga e metabolites tautauā. Tino i roto ia ratou he gidroksiketorolak takiwā me glucuronides. Ratou te tikanga nga whatukuhu (āhua 91%) me te i te whēkau (e pā ana ki 6%).

Ko te hawhe ora o te tarukino i roto i te tūroro ki te mahi noa tākihi ko e pā ana ki 5.4 haora. Kei te mārika i nui haere tenei uara i roto i te paari, me i roto i heke taitamariki.

ate e kore pānga i runga i te hawhe-ora o te tarukino. Me mahara hoki käore te reira e kore e puta i te raau taero i roto i te tukanga o te tātari.

Tuhinga

He aha te tikanga o te tarukino "Ketanov"? Analogues o raau taero, a ko reira rawa e tika ana mō te manawa wā-poto o te mamae o ngā takenga mai.

Ko te kupu, ko te medicament whakaaro whakaritea hoki:

• mamae postoperative (tae atu i muri i te pokanga orthopedic, gynecological me puku);
• niho tunga (tae atu i muri i te pokanga i niho);
• mamae syndromes i muri i te fariiraa i whati, raruraru, me te whara kiko ngohengohe;
• mamae e kulukia;
• syndromes mamae tupu i roto i te osteoarthritis;
• syndromes mamae e meinga pukupuku;
• sciatica.

e matau ana torutoru iwi, engari te whakamahi o papa "Ketanov" me te otinga injectable kahore whakaaturia i roto i syndromes mamae ma'i. He tika anake mo te whakakorenga o te hūhi wā-poto peheé taero. Ka mau i te raau taero i runga o te wā he wā roa rāhuitia te.

contraindications

Ka rite ki te faaineineraa atu rongoa kore-steroidal "Ketanov" whakamahia i roto i te mamae he maha contraindications rerekē. Ko te aha i mua i te whakamahi koe i te reira kia kōrero koe tou tākuta, me te pānui i te tohutohu. tāutu te reira i te contraindications e whai ake nei:

• pāpaka erosive me ulcerative o te wahi gastrointestinal, rawa i roto i te wā whakapeka, hypocoagulation (tae atu hemophilia) me te whewhe keté;
• tūtohutanga nui ake ki te ketorolac manawanui me te tahi atu NSAIDs, bronchospasm, maroketanga, angioedema, ahipirini huangō, hypovolemia (ahakoa o te take o tona takanga);
• ate ranei mate tākihi (i te kore), rawa creatinine wē i te 50 mg / l;
• patunga hemorrhagic (whakapae whakapumautia ranei), hemorrhagic diathesis, nui ake te mōrea o te hohokitanga toto (tae atu i muri i te pokanga), te whakamahi te rere o te tahi atu NSAIDs, hematopoiesis waimaero ranei;
• tau i raro i te 16 tau;
• I roto i te hapū, te tukanga whanau me te wā hohipera;
• Maimoatanga o te mamae ma'i syndromes pūāhua;
• rehunga i mua i pokanga me i roto i a ratou (no o te nui haere tūpono o toto).

E kore e taea e tatou te mea i whakaritea te medicament kaha te ki tūpato i roto i te tūroro ki te cholecystitis, huangō arahau, kore ngakau ma'i, mahi tākihi (wē creatinine iti iho i te 50 mg / l), takawhita, kakā kaha, cholestasis, sepsis, lupus pūnahanaha lupus, me rite i roto i te paari (i runga i te 65 tau) me te hunga ki polyps i roto i te ararewa o te awa ihu me te ihu.

Drug "Ketanov": tohutohu mō te whakamahi

Analogs i rite tikanga o ngā tikanga o te tono, me te inenga. Otiia i roto i te tikanga ki te karo i overdoses te aroaro o ratou te whakamahi tūtohutia te ki te kite i te tākuta.

Me pēhea e inu ahau papa "Ketanov"? Ko te tika tenei ahua o te tarukino ki te tango i te waha (10 mg) kotahi. Ki te tika (hei tauira, ki te mamae syndrome kaha) medicament horopeta e taea te rererua. Heoi, kia tuhia te reira e kore e nui ake te inenga rā o te tarukino 40 mg.

A, no te ingestion o te roanga akoranga tarukino he ra e rima (kore atu).

Ki te hoki tetahi take tetahi manawanui e kore e taea te tango i te ahua-waha o te tarukino ranei (hei tauira, i roto i te aroaro o te erosive ranei pāpaka ulcerative o te puku, whēkau), ka te tautapatia reira he otinga mo werohia. whakahaeretia taua puka te intramuscularly.

I te timatanga o te therapy tarukino whakamahia i roto i te toketaá whai hua iti e kua tīpakohia i runga ki te kaha o syndromes mamae me te whakautu o te manawanui. Ki te tika, whakaritea te manawanui kei a atu Pë opioid.

He waihanga inenga kotahi mo te werohanga intramuscular kotahi:

• iwi i raro i te 65 tau o te tau - e pā ana ki 10-30 mg (i runga i te kaha o te mamae);
• iwi i runga i te 65 nga tau, kia rite ki te pai rite i roto i te tūroro ki te mahi tākihi waimaero - 10-15 mg.

Inenga i muri toutou whakahaere intramuscular:

• iwi ki te 65 - e pā ana ki 10-30 mg, a ka te moni ano nga wha ki te whitu haora;
• iwi pakeke atu i te 65 tau, me te i roto i te tūroro ki te mahi tākihi waimaero - 10-15 mg katoa 4-7 haora.

E kore e nui te inenga rā o te tarukino, i te whakahaere intramuscularly ki ngā pakeke 90 mg. No te tūroro kaumātua me te hunga ki te mahi tākihi waimaero ko reira e tika ana ki te whakaiti i te nui o runga ki te 60 mg. Ko te roanga o te maimoatanga e kore e waiho ra neke atu i rima.

I roto i te whakawhitinga i te whakahaere intramuscular o te raau taero i runga i te rongoā ki te katoa inenga rā o puka e rua e kore e nui ake 90 mg mō ngā pakeke, me te 60 mg mō tūroro paari tūroro ranei ki te mahi tākihi waimaero.

tohu o te tuwhena rawa

I pota teitei o medicament mea i roto i te manawanui e taea te kite ruaki, te mamae puku, mahi tākihi, acidosis pūkoro, whakapairuaki, gastritis erosive me te whewhe keté.

Ka rite ki te maimoatanga o taua tikanga te whakamahi i lavage pekitīlia me introduction o ngā adsorbents. Hoki therapy symptomatic (ie tautoko i te mahi faufaa o te tinana).

taunekeneke tarukino

A, no te te tono tahi o te tarukino i raro i whiriwhiria ki ētahi atu NSAIDs, kia whakawhanake i te manawanui pānga taha o tua, me anticoagulants (tae atu "heparin" i roto i te pota iti me ki "Pentoxifylline") - toto.

Ki te whakamahi te rere o te tarukino arahi ki inhibitors ACE, i reira kia kia kōtītiti i roto i te tākihi.

Me mahara hoki käore te reira e te whakamahi o te raau taero i raro i te arotake, me "Probenecid" faarahi te hawhe-ora o ketorolac me tona kukū i roto i wē.

Ki te tangohia e koe i tenei rongoā ki lithium, he reira taea ki te whakaiti whakawātea tākihi o te konukōhatu me te whakapiki ake i tona kukū i roto i te wē, engari ki "Furosemide" - e tukupu ana tona pānga diuretic.

I roto i te tono o te "Ketorolac" kahore he hiahia hoki tango Pë opioid.

Ko te orotahi pai

"Ketanov" - ko te tino kaha, me te whai hua tenei tarukino analgesic, e te hokona i roto i tata katoa drugstores. Korero o ona analogs, he uaua ki te ingoa i te rongoā whai hua tino. Na reira, hoki te awhina tere o te mamae syndrome maha whakahau kaiwhakaako ki o ratou tūroro ko te tarukino. Otiia ki te hoki etahi take contraindicated te tarukino te ki koutou, tūtohu matou e whakakapi koe i te reira ki "Ketorolac". Tei runga i te utu whenua-kaihanga o tenei taputapu kia rerekē. Ko te utu o te pikau papa Russian tīmata i te 20 moni, Ukrainian - 35, me te Indian - 45.

He aha atu te whakaaro i te tarukino e taea te whakakapi? E whai ia tetahi atu orotahi? "Ketanov" kahore he whakahaunga, ka taea e te hoko tonu e koe i roto i te rongoā. I roto i rite te ara ano e taea e koe te hoko i taua pāpāho rite rite "Adolor", "Torolak", "raau taero Akyular", "Toradol", "Dolak", "Ketofril", "Dolomin", "Ketorolac tromethamine-Farmaplant", "Ketadrop "" Ketorolac tromethamine, "" Ketalgin "," Ketorolac-Eskom "," Ketokam "," Ketorolac-Verte "," Ketolak "," Ketorolac-OBL "," Ketorolac Rompharm "," Ketorol "me etahi atu.

Ko te utu o enei taero e taea e teitei te taketake me te i raro. A haamana'o na e taea te hokona te tarukino "Ketanov" (10 papa) mō te 50-70 moni. kia hoki kia mea te reira e kore e tūtohu reira ki te tango i reira i to ratou ake te ngarahu pai.

E taputapu ki te whakamahi mo te manawa mamae rohe? He reira he ahua ōrite o te "Ketanov" tarukino? (Mea analogs o māngai i roto i te papa kua aroaro i runga) hinu ki te taonga kaha taua he uaua ki te kitea. Heoi, i reira he tonu he tarukino e taea te whakamahi fakahokohoko fakakaveinga. Ko 2% o te rongoā i huaina "Ketorol" (hanga i roto i te India) tenei. Ko te tikanga taua e wātea ana i roto i ngongo 30-karamu, me te hohoro tango tetahi syndromes mamae (ka tono fakahokohoko fakakaveinga).

Reviews o painkillers

Na e matau ana koutou e ko te tarukino "Ketanov", hoki i te tikanga ki te mea i. Me kï reira e he pai tata tūroro Reviews katoa o te medicament. Iwi nei ia wā te whakamahi i papa otinga ranei mo te werohia "Ketanov" kāwanatanga e te tarukino taua tino tere faaore tetahi syndromes mamae.

Ka rite ki whakaaturia e te mahi hauora, te pānga o te faataoto pumau hoki 12-15 haora (i ētahi wā roa). I muri i tenei wa, kia korerotia nga pire (ki te kore e haere te mamae).

Heoi, e kore e taea e kore ki te whakahua i te meka e tenei tarukino, rite tahi atu NSAIDs, i reira te mea he rota o ngā pānga taha. E ai ki ngā whakautu o te tūroro, i ētahi wā i tenei rongoā ai whakapairuaki, me te mamae puku. I roto i tenei take, tūtohu tohunga ki te whakakapi i te ahua-waha o te werohanga tarukino. I muri i te katoa, no te tangata e kore te mea ngaro e taea NSAIDs meinga raruraru nui ki te puku (hei tauira, whai wāhi ki te ahua o keha erosions ranei).

Me mahara hoki käore te reira e e tino maha tūroro pai taputapu utu pūrongo. Whakaaro e he reira e tika ana ki te tango i te tetahi-wā, me te mo te wā poto o te wā, he namunamu ki pire kia nui hoki rawa he wa roa. Ko te taua pā ki te ahua injectable o te tarukino.