Analogs "Ksarelto": utu, tohutohu hoki te whakamahi

Ko tētahi o nga taero, e no ki te rōpū pharmacological o āpiha anticoagulant, te tarukino ko "Ksarelto". inhibits tenei raau tauwehe Xa, a reira, i roto i te tahuri, ko te wāhanga o te prothrombin activator me tetahi o nga wae whakarato coagulation toto wā (pēnei āhuatanga me analogues "Ksarelto").

kawea teie mahana i roto i maha whakamātau horihori ki te unu i te raau taero, e ka whai i te pānga rite me te kupu ki te whakarato i te iti o ngā pānga taha. I muri i kaha wā-kai maha he tauira tika - te tarukino "Pradaksa". Ko te raau - whakakapi anake e tino taea te whakamahi hei utu o "Ksarelto" faaineineraa. E ngā ōrite ki te runga ake, anake te rerekētanga Ko tōna āhuatanga - te ihirangi whakauru hohe, i roto i taka e rua ko e rivaroxaban.

pharmacodynamics

analogues katoa "Ksarelto" i te pānga rite. Ko te mea anake rerekē ratou - te tohu ine, me te kounga o ngā pānga taha. Ko te orotahi tika anake o te raau taero, e kua he pānga rite ki reira, ko te tarukino "Pradaksa".

Tenei tarukino me ona ōrite Russian o "Ksarelto" e hāngai taero tino whiriwhiri e tautāwhi i te mahi o Factor Xa, arā, tautāwhi i te reira. He tenei tarukino he bioavailability waha tiketike, ara Heoi enteral o whakahaere he pokapū ki reira.

tūranga Central i roto i te Niniiraa o tauwehe coagulation X whakahohenga nui te take biotransformation muri Xa mā ara coagulation roto, o waho.

iteraa papû

Tikanga, analogs "Ksarelto" me te faaineineraa ake whakamahia te i roto i te āhuatanga e whai ake nei:

• Prevention me prophylaxis o patu.
• Prevention me te tauturu o te Embolism pūnahanaha.
  
  (I roto i te wā pērā, tohua te medicament e i roto i te tūroro ki te fibrillation Atrial, i te mea takenga kore-valvular.)

• Tangohanga ārai o plugging o thrombi rua hohonu ranei.
• Prevention o hohokitanga o Embolism pūkahukahu.

Drug "Pradaksa", i te mea rite, kua tohua hoki mo te ārai o ngā thromboembolic venous i roto i tūroro hunga i pehia pokanga ki te whakakapi tetahi o nga hononga o nga wahi o raro.

contraindications

Tetahi ōrite Russian "Ksarelto" kua te contraindications e whai ake nei (e taea e ratou rerekē, engari anake ki te whānuitanga iti):

• tūtohutanga mōrearea ranei faaiteraa o tauhohe mate pāwera ki matū roto i te medicament;
• toto hohe e whai informativeness taimaha i te whakamātautau haumanu (hei tauira, toto intracavitary ranei toto i roto i te roro);

• he āhuatanga i roto i nei i reira ko te kaha ake te tūpono o toto rōrahi, hei tauira, i te tukanga whewhe kaha i roto i te wahi gastrointestinal;
• āpiha tarukino therapy e riro āhuatanga rite - ārai coagulation;
• te whakamahi i heparin unfractionated i te horopeta tika mō te mahi pai o te pū tōngāmimi;
• tini o nga mate ate, te whanaketanga o e taea meinga toto o ngā etiology;
• ritenga katoa "Ksarelto" e contraindicated i roto i te tūroro ki te iti hoki tākihi, tupu i roto i tetahi wāhanga;
• reihuka, iti ihirangi o galactose i te tinana;
• hapū me te hohipera;
• i runga i te tarukino me te ngā analogs "Ksarelto" i reira he ano te rohe tau 18+.

Kāwai o tangata nei e tangohia tenei tarukino ki tūpato, me te i raro i te mātakitaki o te mātanga

Ki te tūpato, me te i raro i te mātakitaki o te rata taunaki ana te whakamahi o "Ksarelto" tohutohu mō te whakamahi (rite analogues) i roto i te wā e whai ake nei:

• tūroro peratia nei i te kaha ake te tūpono o te toto i roto i te hanganga;
• tata whakawhiti mate ulcerative he predisposition ki te matahoki;
• maimoatanga o te mate täkihi rerekē nekehanga i roto i ngā ki taero e whakanui i ihirangi rivaroxaban i te tinana o te manawanui;
• Tūroro pangia taero therapy taea o te whakarei ake hemostasis;
• whakatakataka e he ahei o te whakanui ake i te taumata o te rivaroxaban, hei tauira, taero antifungal rōpū azole;
• nga papa tarukino me te orotahi "Ksarelto" e contraindicated i roto i te tūroro ki te HIV, ki te ratou ka mau noa i te whānuitanga o inhibitors protease o te huaketo.

Inu i roto i te hapū, me te ū

Ki te rā, e kore e whakaritea mohiotia te reira, pera me te mana "Ksarelto" analogues o te tarukino i runga i miramira me te haumaru i roto i nga wahine hapu.

Kua whakaaturia ngā i whakahaeretia i runga i te kararehe taiwhanga tāoke korerotia o te taonga kaha o te faaineineraa i runga i kaiao whaea expectant, rite te tarukino ai nui tāoke uri o te tinana wahine.

E ai ki ngā kitenga taiwhanga, te tarukino "Ksarelto" orotahi e he rite ki a ratou o te mahi pharmacological i te kaha ki te whakawhiti i te ewe, na contraindicated te tarukino te.

Ano i roto i te wā o te tono o "Ksarelto" wahine e kore e wareware e pā ana ki te mehua whai hua o te ārai, mai haputanga, e haere tahi i te auau utu o te raau taero, e taea pā tōraro whanaketanga fetal.

whakaaro whakaritenga Whāinga e pā ana ki te pānga o te raau taero e whakamahia ana i roto i te wā hohipera, i kore e te kau te tīariari, engari rangahau taiwhanga i roto i nga kararehe taiwhanga e taonga hohe - rivaroxaban - kua te kaha ki te metabolize me kore excreted i roto i te waiu uma. Na reira, kia kanga whāngai ū te whakamahi o te raau taero.

I runga i nga raraunga i homai e rangahau taiwhanga, ka taea e tatou te mea e kore e rivaroxaban pā te kaha o te rauropi pakeke ki te waihanga uri taea i roto i kiore, engari i roto i te tangata i tenei ahua o ngā kua whakahaere.

Pākia me te whakakorenga ara

Hoki fariiraa enteral reira e toru ara o tupuranga, e hāngai ana ki tetahi toru o te katoa maha o tarukino kore-metabolized:

• excretion mimi;
• excretion i roto i te feces;
• whakakorenga mā rārangi papī tākihi (i roto i tenei take, tata kore rawa metabolized ka whakakorea i roto i te puka, nā).

Biotransformation rivaroksaba whakamana e tikanga e he motuhake o te pūnaha cytochrome.

Ko te ara matua - te piti hāora o te rōpū morpholino me hoki te roha o te here amide ki te wai.

Akoranga whakahaere i roto i te vitro, taea te whakawa i taua rivaroxaban ko te pūtake mo te P-glycoprotein me te pūmua e whakarato ātete mate uma oncological.

Tikanga, kawea tango o metabolites te i te wā 5-9 haora.

pānga taha

ta ia ki te faaineineraa tohutohu mō te whakamahi: kia analogues "Ksarelto" rongoā whaiaro ranei kia tangohia anake i runga i whakahaunga. Ko te ako ano whakaahua ana i roto i te taipitopito te inenga o te raau taero, ona analogues ranei. Kia tino ki te pānui i te fariiraa ako!

Kei raro whakaata tukanga e hiahiatia katoa me tauhohe i i tarukino "Ksarelto" analogs. pire Price - i 900 moni. Ko reira ngāwari ka whakaaro koutou e te nuinga o ngā pānga taha he okotahi ki te ture.

• pānga te taha e kua rite ina whakamatautau toto me te pūnaha lymphatic, he anemia me thrombocythemia, e kitea pinepine.
• Tachycardia - anake te tauhohenga kino, ka tango i tēnei tarukino.
• Toto.

Ko nga ngā contraindications ki te tarukino "Ksarelto" te ako enei.

Analogs o tenei tarukino kia meinga he arā o te wahi kūnatu: toto, mamae paetata, tohu dyspeptic, ētahi wā - mangai maroke.

Nā ki te whakataki o tauhohe rohe rivaroxaban taea puta: kirika, pupuhi i te wāhi i werohia, ka whakahaere tikanga parenterally, ngoikore, me te ahuatanga.

whai wāhi te putanga o enei tukanga ki te faaineineraa "Ksarelto" ritenga. Ko te utu o te raau taero, rite ki te tikanga, he paerewa i runga i mekameka rongoā katoa.

Methods o Whakamahi ko Inenga

ngā mōhiohio Taipitopito e pā ana ki te fariiraa tika e taea te whakarato ki te tarukino rānei tino "Ksarelto" ako. e kore te mea faufaa rerekē analogues o te tarukino faatura tenei i roto i.

E wātea ana i roto i te puka papa tenei tarukino, na tangohia pire te enterally. Ki te kore e taea e te manawanui mo etahi take horomia te papa - ka taea te hurihia ana a whakauru ki te wai e tika ana (tea, te wai).

I muri i te fariiraa i tenei tarukino kia whai tonu te kai.

tuwhena rawa

Kore ki te ū ki te tikanga fariiraa "Ksarelto" tuwhena rawa taea, e e te tikanga tukinotia symptomatically, rite te tarukino he raau motuhake.

I roto i te tikanga ki te whakaiti i adsorption o te raau taero i roto i te kōpiro iti taea e tetahi sorbent, pērā i te waro whakahohe. Hoki ki te whakatere excretion o metabolites tika ki te whakarato diuresis i akina atu, kawea nei i roto i mā te whakamahi o moni nui o te wai, me te whakamahi o Diuretics.

utu

Tei runga i te kaiwhakanao, te utu ko rerekē "Ksarelto" tarukino i 899,00 moni. mo 10 papa, e roto i 10 mg o whakauru kaha, ki 1740,49 RUB.

Mōkihi, i roto i nei 30 pire, e taea te hokona hoki 3300,00 moni.

Ko te mōkihi nui kei 100 capsules, utu reira 8600 moni.

Kaupapahere Pricing tei "Pradaksa" tarukino i runga i te ihirangi ine o te whakauru kaha ia capsule:

• 75 mg - 716,00 horoitanga;.
• 110 mg - 1574,00 horoitanga;.
• 150 mg - 1676,00 te horoitanga i.