"Farmadipin" (pata) i te aha?

I tēnei wā, i reira e maha rongoā rerekē mō te takawhita me stenokardicheskie patua. Ko tētahi o ratou ko ano hoki pērā i "Farmadipin" (pata) rongoā. He aha e tenei tarukino, kōrero atu i roto i te taipitopito.

hanganga

Te whakauru mātātoa i roto i tenei take, ko te nifedipine (nifedipine). 1 ml o tenei otinga, ko te reira i roto i te nui tetahi. Ara, i 100%, e hāngai ana i runga i te maroke-momo taonga - 20 mg. Huri i te reira e toru tekau pata.

"Farmadipin" (rūrūtia), te ako ki ai ka te tono kia kōrero i raro nei, i roto i te hanganga ko te aroaro o ngā matū ngaahi houalotú pērā i polyethylene glycol 400 me 96% ewaro.

āhuatanga pharmacological

kua he pharmacodynamics i rawe ki tenei tarukino. Ka rite ki kua whakahuatia i runga ake, te "Farmadipin" (pata) kei taonga nifedipine e whakarato antihypertensive me anti-anginal mahi. whakatairanga ārai te reira i te urunga o ngā katote konupūmā ki cardiomyocytes me ngā pūtau uaua maeneene i roto i etahi pera piringa, me te coronary roto i te ngaohiko-momo takere mahi puhoi o kiriuhi pūtau. Tenei taonga nui. whakarato hoki Nifedipine whakangā o te uaua maeneene iaia, nui haere piringa me ngā iatuku pūngākau, te whakakorenga o mamae. whakaiti tenei pēhanga toto, ātete iaia pūnahanaha, afterload cardiac me te tono hāora myocardial. Ano, ka tango i tenei tarukino tonu ki te whakaatu i etahi tohu. Ara, i reira te mea he heke iti i roto i te contractility myocardial me mahi ngakau, me te ahua iti whakahiato mōtepe.

Pharmacokinetics

I roto i tenei whakaaro, "Farmadipin" (pata), whakaaro nei i roto i tenei pūrongo tohutohu mō te whakamahi, he ona ake āhuatanga. A, no te i ia he fariiraa ā-i roto i te wahi kūnatu pai whenumi. Ko tōna bioavailability Ko e pā ana ki 40-60 ōrau. He pānga whanaketanga ngā tere (i muri i 5-10 min) kitea i roto i te whakatinanatanga o te whakahaere sublingual. He mea nui ki te mohio. Tikanga, kite te pānga rahi, kei roto i te 30-40 meneti. e kore te whakatinanatanga o te ingestion ngā pā i te tere o te absorption o te kaihoko. Ka tohe te faaiteraa o te pānga hemodynamic mō te 4-6 haora. Ko te kupu 90 ōrau o te nifedipine herea ki pūmua toto wē. metabolized reira taua faaineineraa rite "Farmadipin" (te maturuturunga iho) i roto i te ate. Ko te aroaro o te whakawātea katoa o nifedipine ko i 0.4 ki te 0.6 l / kg / hr. Kei te whakapae te reira i te tinana te nuinga rite metabolites momo tautauā. Ko te wā o te hawhe-ora kia rerekē i te 2 ki te 4 haora. I roto i te kaumātua, me ngā tūroro ki cirrhosis o te ate, pākia nifedipine pōturi iho tino. Ka rite ki te hua, to ratou e taea te nui haere hawhe-ora o nga tikanga tohu āhua 2-taiepa. I roto i tenei take, ko te mea e tika ana ki te whakaiti i te horopeta, me whakapiki ake i te wā i waenganui i pōhiri o waihanga mea. e kore e cumulated Nifedipinv tinana. Hoki e taea e te reira i roto i te nui iti tomo i te toto-roro me te arai placental. I roto i tenei take, kua excreted reira i roto i te waiu uma.

Tuhinga

Whakaritea "Farmadipin" (te maturuturunga iho) i roto i te wā e whai ake nei:

• I roto i te kaupapa o te takawhita faufaa, me te symptomatic.
• Hoki te maimoatanga me te ārai stenokardicheskie patua.
• cardiomyopathy A, no te hypertrophic.
• A, no te mate o Raynaud.

tono

Tangohia "Farmadipin" (pata) sublingually. A, no te te ara koi i roto i te pēhanga toto (hei tauira, 180 / 100-190 / 110 mm HG. V.), He horopeta tuatahi kotahi o te tarukino hoki pakeke te tikanga ko āhua 3-5 pata (2-3,35 mg). Tūroro ki tau matatau te whakaritea hoki he inenga motuhake. Ara - kore ake atu i te 3 pata (e pā ana ki 2 mg). Ano, Ka taea e te tokomaha i tohua maturuturu i runga i te wahi iti o te taro maroke te huka ranei. kia mau rite te roa rite taea tona manawanui i roto i te mangai. Ki te inenga iti hua o te raau taero nui haere te āta tae noa miramira haumanu. I roto i tenei take, i te reira katoa tei runga i te takitahi. I nga faaiteraa muri o te pēhanga toto te whakanui ake kia arata'ihia ïa ki te horopeta i whakaritea. Ano, i reira he tetahi paearu motuhake. takoto te reira i roto i te meka e ki te whakatika i te pēhanga toto ki te 190 / 100-220 / 110 mm HG. v., ka tango i te pata tarukino taea te āta nui haere ki te 10-15 (6,7-10 mg). kia tango te reira i ki pūkete te huringa i roto i te pēhanga i roto i te manawanui i homai. He mea nui ki te mohio.

Me hoki koe ki te tango ki roto ki pūkete te aroaro o nui haere te tūtohutanga i roto i te tahi mau tūroro ki tenei tarukino rite "Farmadipin" (pata), e te hunga pai arotake. I roto i ngā take pēnei, tīpakohia te inenga te takitahi. Tīmata ki te 3 pata, a ka āta whakaarahia ki 2-3 (1,34-2 mg) tae noa ki te kau, ka tutuki te pānga haumanu hiahiatia te.

Kia mahara te reira e i roto i te taikaha o te horopeta tuatahi o te tarukino e taea meinga he hekenga koi i roto i te pēhanga toto!

pānga taha

I roto i te tono o tenei faaineineraa rite "Farmadipin" (te maturuturunga iho o te pēhanga), i reira kia kia tohumate o whakapairuaki, tachycardia, hypotension, "tai" o toto ki te mata. I roto i ētahi wā, kia meinga tauhohe mate pāwera i roto i te puka o te waewae edema, ohorere kiri. kia hoki whakaatu ratou tohu o te ngoikore, whanoke, ānini.

contraindications

riria te fariiraa o te tarukino taua, rite he "Farmadipin" (te maturuturunga iho) te ki te kawe i roto i te aroaro o nui haere te tūtohutanga ki ona wāhanga, ru cardiogenic, te pūtahi o nui, me te stenosis mitral, hypotension, tachycardia, me te i roto i te hapū, me te hohipera.

tuwhena rawa

I roto i tenei take, kia puta etahi o nga tohu kino. Ara taea te haere tahi tuwhena rawa o taua raau taero rite "Farmadipin" (pata), e te takanga o te kore ngakau, ru, acidosis pūkoro tinana me haehae, he te maturuturunga iho koi i roto i te pēhanga toto. A, no te he e tika ana te faaiteraa o enei tohu ki te huihui ki etahi mehua akiaki o āwhina. ngā ratou i roto i te lavage pekitīlia, waro whakahohe, konupūmā pūhaumāota me te sympathomimetics introduction, therapy symptomatic.

whakamahi Āhuatanga

"Farmadipin" (te maturuturunga iho o te pēhanga) whakakapi mo ki te tono i reira anake ki aroturuki haumanu tupato o tūroro ruhiruhia me tūroro e whai ranei:

- angina iu.

- kore nui ngakau.

- cardiomyopathy hypertrophic.

- Koi stenosis te pūtahi o.

- nui takawhita pūkahukahu.

- patunga whakapeka.

- Mate huka mellitus.

- mahi Renal me te ate.

kia whakaturia te inenga o te tahi atu rongoā e whakamahia ana ki te nifedipine takitahi. glycosides cardiac taea te whakamahi hoki i roto i te fariiraa o taua rongoā rite "Farmadipin" (pata), analogs nei e whakaaturia ana i raro nei i roto i tenei kuputuhi.

Ki runga ki te fariiraa i te tono tukutahi o nifedipine ki ngāwhā konupora rō-uaua Me wahine hapu ki te faaohipa aroturuki tupato o te pēhanga toto. kia meatia tenei no te mea i reira te mea he pea o tukupu pēhanga toto e taea kino e rua whaea me te kukune.

Tūroro ki taumahinga ate waimaero, e rapu ana hoki aroturuki tupato. I roto i ngā take kino, kia heke te horopeta.

tsitohromichnuyu Nifedipine metabolized mā te pūnaha P450 3A4. Ka rite ki te hua, kia raau taero e tautāwhi i häpaingia te paru rohe tohua ranei e whakarereketia te pānga o "tuku tuatahi" whakawātea o te taonga ranei. Ki te whakamahi te rere o te nifedipine ki taero o tenei momo kia whakahaeretia te pēhanga toto. Ki te tika, kia huihui ki te whakaiti i roto i te inenga o te tarukino, rite "Farmadipin" (pata).

Kua whakakitea whakahaere ngā motuhake i roto i te vitro te hononga i waenganui i te whakamahi o te raveraa ra konupūmā i roto i tenei nifedipine take me te matüora huringa kōaro spermatozoa pa ana te ino o te kaha o te whakamutunga ki te whakatinana i te kikiritanga.

Tango "Farmadipin" (pata), kia whakamanawanui ai i ngā mahi momo pea mōrearea, tono aro nui. Ara, ka kore te mea e tika ana ki te pei waka, me te mahi ki ētahi atu pūhanga, a na i runga i.

pāhekoheko

"Farmadipin" (droplet) he mahi hypotensive. Tenei āhuatanga whakarei ake i te raau taero i blockers kāwai. Ko, "Farmadipin" (te maturuturunga iho) faarahi β-adrenergic pānga, Diuretics, pūhau, me ētahi atu antihypertensive āpiha, taka me inu kei roto waipiro, pōuritanga tricyclic. I roto i ētahi wā, te whakaiti nifedipine te kukū quinidine i roto i te wē toto. Ko te whakakorenga o tona nui whakanuia ana te reira. Ko te kupu, tūtohutia te whakamahi i te therapy ngā te ki te aroturuki i te taumata o te quinidine kukū i roto i te wē toto.

"Diltiazem" whakaiti i te whakawātea o te tarukino rite "Farmadipin" (rūrūtia). "Fentanyl" tino whakarei ake te faaiteraa o te pānga hypotensive. Ka rite ki te hua, i mua ki te whakahaere o te tarukino (i roto i iti iho i te 36 haora.) Kia mutu fariiraa "Farmadipina". whakamahi tahi o te β-blockers ki nifedipine kia arahi ki hypotension. "Farmadipin" (makaka) whakapiki i te kukū o te theophylline, carbamazepine me te digoxin i roto i te toto. "Rifampicin" arata'i ki he vaivai o te pānga haumanu o nifedipine, ko te kupu horo ake te whakahaere o tona pākia. "Cimetidine" whakarei ake kukū "Farmadipina" i roto i te wē toto.

Ngā me tikanga o te rokiroki

I roto i tenei take, i reira e etahi paearu. Store "Farmadipin" (te maturuturunga iho) Me kia i te pāmahana rūma i roto i te wahi maroke. Me tiaki te tarukino i te marama, me te taea o ngā tamariki. Kei te hangaia Storage o tenei tarukino hoki ki runga ki te 1 tau, me te 6 marama. Kia whakatuwheratia te oko - 28 ra.

hararei

"Farmadipin" (makaka) e taea te mohio anake i te whakahaunga.

tarapēke

I roto i te oko o te 25 ml 5 ml ranei. haumi ratou i roto i te mōkihi.

"Farmadipin" (pata) analogues i Russia

He maha utu mo te tarukino. Ko te hunga matua ko:

- "cordipin".

- "Nifedipine".

- "Adalat".

- "Kordafleks".

- "Corinfar Uno".

- "Kordafleks RD".

- "fenigidin".

- "Osmo-Adalat".

- "ia faataere cordipin."

- "xl cordipin".

mutunga

Na e matau ana koutou ki ta te pērā i "Farmadipin" (te maturuturunga iho) te rongoā, i nei e tauturu te reira me aha ngā āhuatanga. I roto i tetahi take, i mua i te tango i tenei tarukino kia kōrero te tākuta tohu.