Hua "Levodopa": tohutohu mō te whakamahi, whakaahuatanga, hanganga, analogs me arotake

He aha te mea te tarukino "Levodopa"? Tohutohu mō te whakamahi, utu, ka kia kōrero te iti atu arotake e pā ana ki te tarukino. Ka ako ano hoki koe e pā ana ki te mea kei te whakaritea i tenei rongoā, ki te i ia tetahi tauhohe kino me contraindications, i roto i nei hanga ko reira e wātea ana mō te hoko, ngā nei i roto i tona hanganga, a na i runga i.

Te hanganga, te āhua, whakaahuatanga

E wāhanga Kei te tarukino "Levodopa"? Tohutohu mō te whakamahi tohu e te whakauru kaha o te tarukino he levodopa. I roto i te hoko ko te reira i roto i te puka o papa spigot porohita tae ma, tākai i roto i ngā pouaka aratau pūtau me te pepa, aua.

Ko te parau tumu o te mahi o te medicament

tarukino "Levodopa" pehea e mahi i te reira? Tohutohu mō te whakamahi, kua korerotia arotake e tenei huinga kaihoko antiparkinsonian. E whai ana ki te whakakore i te rigidity, hypokinesia, faaati, e waiwai ana me te dysphagia.

I roto i te tinana, kei te tahuri mahi wāhanga rongoā ki dopamine (CNS), reira hanga ake te kaimahi o te huānga.

Dopamine e puta i roto i te kopa piringa, whakaatu kahore pānga anti-Parkinson o levodopa. Ko e tika ana ki te meka e kore e tomo te reira i te pūnaha io pokapū, me te ko te take nui o tauhohe kino o te tarukino tenei.

Ki te whakaiti i te horopeta o te taonga kaha i roto i te tinana tangata faataahia te medicament i roto i ngā ki inhibitors piringa dopa-decarboxylase. āwhina ana tēnei tikanga ki te whakaiti i te pānga taha i tango i te pire.

Pharmacokinetics

Kia pehea te nui rongoā whenumi te "Levodopa"? Tohutohu i runga i nga āhua tono e i muri i whiwhi i te raau taero ki te tinana reira kei te tino tere whenumi i te whēkau.

Absorption o te taonga kaha ko e pā ana ki 20-30%. I roto i tenei pānga haumanu i kitea i muri e pā ana ki 3 h.

horomanga Food (tae atu etahi kai) tika pānga te absorption o te tarukino.

Kei te metabolized te tarukino, reira hanga e rave rahi metabolites. Excretion o te taonga kaha e wahi i roto i nga whatukuhu, me roto i te whēkau.

Tuhinga

I raro i te mea i whakaritea tikanga tūroro te tarukino "Levodopa"? Tohutohu mō te whakamahi rite ki nga tohu e whai ake nei:

• syndrome postencephalitic e puta i roto i mate iaia roro haurangi paitini ranei;
• syndrome o Parkinson, ano, i meinga e te whakamahi o te raau taero ähotea;
• mate a Parkinson.

contraindications

Ahakoa i reira he contraindications i roto i "L-dopa" tarukino? Tohutohu mō te whakamahi pūrongo e riria tenei rongoā te ki te tango i roto i te wā e whai ake nei:

• hypersensitivity ki te wāhanga;
• ngā ki inhibitors Mao;
• i roto i te hapū, me te i roto i te uma-kai he pēpi;
• tūroro i raro i 18 tau.

Ki te tiaki nui e taea te whakaritea te tarukino i:

• emphysema;
• aroaro o te mate pūkahukahu, mate ngakau, ate me te endocrine pūnaha me kuhunga;
• huangō arahau;
• faaiteraa o te āhotea;
• tonapuku (tae atu hītori);
• koki-katinga papahewa;
• haurangi auau (haehae);
• papahewa tuwhera-koki, i puta i roto i te puka ma'i;
• täkihi me te ate kore;
• infarction myocardial (hītori), a hoki i roto i ngā o ngā momo o arrhythmias;
• whewhe duodenal me te puku;
• CNS faaiteraa o te tukino;
• raruraru manawataki ngakau.

Ko te tarukino ko "L-dopa": tohutohu mō te whakamahi

Kua Whakaahuatanga o te tarukino kua aroaro i runga ake. Ka rite ki kia waiho te reira?

E ai ki nga tohutohu, tangohia te tarukino te waha. Kei te āta nui haere te inenga i te iti ki te mōrahi (i runga i te manawanui takitahi).

Started maimoatanga ki te horopeta o 0.25-1 g te wehea tenei moni ki toru nga wahi. Kei te āta te inenga nui haere ki te 0,125-0,75 g E i te reira i rite wā o te wā (hei tauira, e toru nga ra), e arotahi ana ki te whakautu o te manawanui takitahi, ki runga ki te kau, ka e kia kitea te pānga tino arotau i te therapy.

Ko te horopeta mōrahi ia ra e kore e nui ake waru karamu.

Rongoā i roto i tetahi take, e kore e whakakore koi. Kāti tango i te reira āta.

tauhohe kino

E nga pānga taha o te tarukino "Levodopa"? kī Tohutohu mō te Whakamahi e i roto i te horopaki o tona fariiraa i te tangata kia wheako etahi tauhohe kino e pā te mahi o ngā pūnaha katoa o te tinana:

• pūnaha Cardiovascular: palpitations ngakau, arrhythmia, ngangau o te pēhanga, tauhohe orthostatic, syncope, a na i runga i.
• wahi kūnatu: korere, ruaki, dyspepsia, anorexia, kōroke, huringa i roto i te reka, mangai maroke, toto i te wahi gastrointestinal.

Me mahara hoki käore te reira e kore waho tauhohe taha e pa ana i te mahi o te hematopoiesis, mimi, romahā, me ngā pūnaha io. E mea pinepine i roto i te tūroro te fariiraa i tenei tarukino mate pāwera puta, huringa i roto i ngā tawhā taiwhanga me ngā pānga houhou i runga i te kiri.

Kēhi o tuwhena rawa (tohumate, maimoatanga)

I roto i te tono pota tiketike whakakitea he whakarei nui o ngā pānga taha. Taua tikanga rapu maimoatanga i roto i te puka o te lavage, aroturuki huru whānui o te manawanui me te mahi o te ngakau. Ki te tika, te kawe i roto i therapy antiarrhythmic.

taunekeneke tarukino

fariiraa tukutahi, me te whakaaro o te faaineineraa "ditilina" beta-agonists, me āpiha e kua tikanga mo te inhalation rehunga, faarahi te tūponotanga o arrhythmias o te ngakau.

Bioavailability "Levodopa" taea te whakaiti i te pōuritanga tricyclic.

Ko te huinga o te tarukino ki "thioxanthenes," "Diazepam" ähotea "Phenytoin" m-holinoblokatorami "clonidine", "Difenilbutilpiperidinom" "Papaverine", "Clozapine", "phenothiazine" "pyridoxine" me "reserpine" tino maha whakaiti reira tona pānga antiparkinsonian.

formulations konukōhatu ake i te tūponotanga o te takanga o dyskinesias me moemoea, a whakanuia ana "methyldopa" medicament tauhohe taha.

Ko te huinga o Mao inhibitors me "Levodopa" arata'i ki tohanga waimaero. I roto i tenei whakaaro, kia te wā i waenganui i pota o enei rongoā i te iti rawa 14 ra.

whakaiti i tohua i roto i te pēhanga kitea ki te huinga o te rongoā, me te whakaaro "tubocurarine".

Drug "metoclopramide" te whakanui ake bioavailability "Levodopa" tere te putu i pekitīlia. pēhia kia tenei pā te akoranga o te mate.

tūtohutanga motuhake mō te whakamahi o te raau taero

He aha e hiahia ana koe ki te mohio i mua i te tango i te papa "Levodopa"? Tohutohu mō te whakamahi (te utu i raro) faaara e pā ana ki te riri ki te hauora i te whakakorenga ohorere o te medicament.

I roto i te wā i reira e kore e taea ki te karo i te whakaiti o te inenga withdrawal o rongoā ranei rapu aroturuki auau o huru o te manawanui.

I mua kahore e tūtohu te tarukino ki pau ngā kai taonga i roto i te pūmua, mai te whakaiti reira te absorbability o te taonga kaha.

titau te therapy aroturuki tonu o te ngā pūnaha, whēkau, me ngā tawhā toto.

Utu me analogues

Ko te tata analogues "L-dopa" teuteu tikanga he pērā i te "benserazide levodopa" me "Levodopa Carbidopa". Tohutohu mō te whakamahi pūrongo e enei taero i te taua tohu, ngā pānga taha, huarahi o te mahi me te contraindications. Ko te rerekētanga anake i waenganui i enei moni ko ratou hanganga.

Taua matū kaha pērā i carbidopa me benserazide whakaiti i te hanga o te dopamine i kiko piringa, reira te whakanui ake i te nui o levodopa tomo te CNS.

Ko te kupu, humarie taea tuhia te reira e prescriptions "Levodopa Carbidopa" me "benserazide levodopa" (tohutohu mō te whakamahi o e tāmau ano i roto i te tākai i enei tikanga) faaore inhibitors fariiraa atu piringa dopa-decarboxylase.

Ko te tahi atu hoa, na te muri ngā taua raau taero rite "ışık Meath", "Tremonorm", "Dopar 275", "Tidomet", "Duellin ',' Sinemet ',' Zimoks", "Sindopa", "ışık" "Lac". Me whakarite rātou i tākuta anake.

Ko te utu o "Levodopa" te tarukino Ko te tino nui. I roto i pharmacies, ka taea e koe te hoko i tenei rongoā i roto i 1500-1850 moni.

Reviews rongoā

kia kawea maimoatanga o tetahi mate i roto i anake mo te whakaaro o te rata mātanga. Na Parkinson o he kahore okotahi.

Tūroro e ka mau te tarukino "Levodopa" i roto i ona whakaaro anake, a kahore e whai i te pānga pai haumanu. Na maha e kino tenei arotake medicament. Kua korerotia Kaiwhakamahi e ara ki te whakamahi roa o rongoā kua kitea te pai whakapainga nui.

Ki te tangohia te rongoā i raro i whakaarohia e te kaupapa, i whakawhanakehia e te ngaio mātanga te whai i te akoranga o te mate, he angitu tata tonu te tukanga maimoatanga. Ko e tika ana ki te meka e me tangohia te tarukino kaha i roto i te inenga tino, e tei runga i te manawanui tenei, nga āhuatanga o te mate, me te tahi atu āhuatanga.

Kei te tino tūroro tautuku ki te talena maimoatanga, kua korerotia e te tarukino "Levodopa" Ko te tino whai hua i roto i te whakakore i ngā raruraru hauora.

I roto i te meka, he tokomaha amuamu e pā ana ki te utu nui o te rongoā. Heoi, titau tohunga e te utu o tenei tarukino ko tino tika.