"Klarotadin": tohutohu mō te whakamahi. Hea ki te hoko "Klarotadin"? Mai i te mea pire "Klarotadin"? Analogs "Klarotadina"

mate pāwera - ko rawa hāngai te kaupapa, rawa hoki ngā mātua. I muri i te katoa, kei te piki haere te maha o na-ka karanga "Allergy" nga tau. Na reira, whakaaro inaianei tatou i roto i te taipitopito te faaineineraa "Klarotadin". ka timata tohutohu mō te whakamahi i to tatou arotake o te tarukino. Utu ki te kite i te reira i mua i te whakamahi. Hokona "Klarotadin" i tetahi rongoā i roto i to koutou pa, me kahore te whakahaunga.

ka ki te tono

Ka taea te whakamahi i te medicament i pīkaru mate pāwera, angioedema, me urticaria (whakapeka ma'i me idiopathic). Ko whai hua i roto i te tau-a tawhio Rhinitis kaupeka ranei ano te tarukino "Klarotadin"; tukua te pseudoallergic ina e meinga tauhohe i te histamine; tauhohenga ki te pepeke ngau rerekē; me te dermatoses apohia e. kia kō atu i te rārangi.

Aha hua te

A feruri te tuatahi te hua "Klarotadin" -sirop. i runga i te tono o ana tohutohu, ka hoatu i raro nei. Inenga - 5 mg / 5 ml. Loratodina (whakauru kaha) kotahi koma haumano ia ritamano o te tirikara. Excipients: propylene glycol, te huka, waikawa-mangeo, Ethyl waipiro, waikawa citric, tropeolin, wai e purea ana, flavorings kai.

Hokona i roto i te pounamu o te karaihe pouri, te kaha o e kotahi rau milliliters. Ko tenei mirumiru i roto i te pouaka pepa. Ko te kete hoki ngā te koko ruri motuhake.

Na whakaaroa te pire "Klarotadin". Ia papa e tekau milligrams loratodina. Mai i pŭpŭ tauturu - MCC, reihuka, konupūmā stearate, glycolate, māngaro konutai. Whakanohoia i roto i te opupu, ia ki whitu tekau ranei nga wahi. pea te kātene i tetahi ki te toru-mōkihi o paraharaha.

pharmacodynamics

no tenei tarukino ki te H1-antihistamines, e kahore anticholinergic me mahi pokapū. Tīmata i roto i te hawhe haora i muri i te inu, me te mahi puta noa i te ra. He mea nui kia kore e te whakahaere ma'i o te tarukino whakawhanake ātete ki reira. Me kï reira e kore te taonga loratodin me ona metabolites e taea ki te tomo i te BBB.

Pharmacokinetics

Ka rite ki mo te horomanga, i roto i te rōpū i roto i te pota tūtohutia e te kaiwhakanao, loratodin hohoro a tino whenumi te wāhanga matua ki te bloodstream i roto i te wahi gastrointestinal. Ko te kukū o e taea kua whakatau, puta i roto i te hanganga o te wē toto rima meneti i muri i te kai. Ko te wa ki te tae Cmax i wē loratodina, rerekē te reira i tetahi haora e wha tekau miniti ki te rua haora toru tekau meneti.

Ko te wa ki te tae Cmax tona metabolite kaha ko e pā ana ki te toru haora. kia mau Just i roto i te ngakau e taea ki te pōturi iho te paetae Cmax loratodina me tona metabolite kaha i roto i te wē mo kotahi haora te whakamahi tukutahi o kai tahi me te rongoā, ko te. I te wa ano e kia tonu Cmax o enei matū, me te taea i roto i tetahi ara ki te whakaawe i te putanga i te kai, ko te.

Na te kaumātua. "Klarotadin" (ako i runga i te tuhipoka tono), e taea te tango ratou, kahore tetahi rahuitia motuhake e pā ana ki te tau. kia mau Just i roto i te ngakau e nui haere te wa ki te tae Cmax e haora kotahi me te hawhe, i roto i te rerekē ki te iwi taitamariki. Ki te whakaute ki te kino ate waipiro, i runga i te pakeke o te mate rānei i te whakatutuki hoki nui ake Cmax.

I roto i te ihirangi wē toto loratodina tona metabolite kaha tae te nuinga o tūroro taumata pahoho i te rima i muri i ingestion te ra. He here ki pūmua wē - 97%.

pākia

metabolized te ate loratodin taonga kaha te ki te hanga i te dezkarboetoksiloratadina metabolite hohe. puta tenei e tika ana ki te mana o te cytochrome P450 isoenzyme CYP3A4. pā hoki Pānga cytochrome P450 isoenzyme CYP2D6, ahakoa ki te whānuitanga iti. Kektonazol hakari, ko te inhibitor o CYP3A4, taea reira tahuri loratodinu ki dezkarboetoksiloratadin. Ko e tika ana ki te pānga o CYP2D6 tenei.

tupuranga

Unu o te tarukino "Klarotadin" (tohutohu mō te whakamahi, me te reira e whakahuatia) mā te whatukuhu, me te tahi ki te ate. Ko te toharite T1 / 2 loratadine taonga he waru haora, me te rua tekau meneti (kia whānui i toru ki te rua tekau haora). Ki te whakaaro ki te metabolite kaha, tona toharite ko rua tekau-waru haora (ka taea e ngā i ono haora e wha tekau meneti, me te toru tekau whitu haora).

Ko te dezkaboetoksiloratadina waenga ko te whitu haora, me te toru tekau meneti (ngā, tahi ki te toru tekau ma waru haora). Ki te mea te reira te waipiro ate lesion, te T1 / 2 ka nui ake ki te whakanui ake i te pakeke o te mate. Otiia i roto i te tūroro e whai i te hēnga o ōna whatukuhu, i te pahua tātari toto, pharmacokinetics kore tino ke.

hapūtanga

e kore e taea te tango te reira e te wahine hapu te raau taero, no te mea e taea "Klarotadin" tamariki e kei roto i te kopu, meinga kino. Ki te meinga e tika ana ki te whakamahi i tenei whaea tarukino te u, na ko reira tika ki te mutu whāngai ū rite te roa rite oti te maimoatanga te.

contraindications

Ka rite ki ki ētahi atu taero he contraindications me "Klarotadin". Tohutohu i runga i te tono ta e kore kia whakamahia te tarukino, ki te he hypersensitivity ki tetahi wae o tenei faaineineraa te manawanui. He huru i roto i nei e kore te te taputapu whakaritea riro ranei ano Pregnancy me hohipera. Tūroro e whai kore ate, i ki te tango i te tarukino "Klarotadin" ki te tūpato.

pānga taha

Na ko reira tika ki te korero ki e pā ana ki te āhua o tenei kia pēhia ngā te tarukino i runga i te tinana tangata. tohu pea o disorders pūnaha io, ara, manukanuka, asthenia, hyperkinesia, rōpū, o te tamaiti, somnolence, faaati, paresthesias, whārua me te mate wareware. ngako subcutaneous me te kiri kia whakautu ki ngā wāhanga rongoā dermatitis.

Ki te kōrero tatou e pā ana ki te pūnaha genitourinary, ka i runga i tona wahi kia he huringa i roto i te tae o te mimi, kia whawha te manawanui te inanga, ki te mimi, ka e kia haere tahi i te mamae. kia hoki whakawhanake te reira i vaginitis, dysmenorrhea me menorrhagia.

I runga i te wahi o te pūnaha endocrine me maumaui taea. Ka taea te nui haere Weight, ka ite matewai te manawanui, a kia whakapiki ake i te reira sweating. kia hoki pūnaha musculoskeletal amohia e te tahi mau kōtītiti i roto i to ratou mahi. Tenei cramps waewae me te myalgia, me arthralgia.

Ka taea hoki mamae te pūnaha kūnatu. Distortion o reka, te kōroke ranei korere, anorexia, gastritis, tokopā, nui haere te hiahia, stomatitis me te flatulence - katoa o tenei ki te tetahi tūponotanga kia puta ka te whakamahi i te "Klarotadina".

E pängia ana ki te kore, me te pūnaha romahā. ka whakaatu maumaui rite bronchoconstriction, mare, pakohu kakā, me te maroke o te membrane mucous i roto i te ihu. Ka taea e hoki whakawhanake pīkaru, kite ohorere, mamae i roto i te taringa me te kanohi. Ko te kaupapa ki te taha pānga e kia whakaatu rite palpitations, pēhanga toto nui haere, ka whakaiti i te reira hoki te pūnaha Cardiovascular.

Kēhi o mate pāwera, whakakitea i roto i te puka angioedema, pruritus, urticaria me te photosensitivity. kia hoki riro hoki koe te mamae, kirika, whango, mamae pouaka, Chills, blepharospasm, me te mamae uma.

Ka rite ki a koutou e taea te kite, ka taea e te pānga taha kia tino nui, kia kaua e kore e wareware e pā ana ki reira. hiahiatia kōrero e rua i mua i te whakahaere tuatahi o te tarukino me te i roto i te take o te rapunga i te raruraru i runga.

Whakamahi, me te inenga

Tirikara me papa "Klarotadin" i nei - ki te matau. Na kia kōrero a pā ana ki te pehea kia te reira e tangohia. E te tikanga ēnei taero mō te whakamahi ā-. Tamariki e he pakeke atu i ma rua nga tau, me te tūtohutia horomanga rā o te pakeke, ko te tekau milligrams. Tenei rua scoops tirikara wai ranei kotahi papa. Ko tamariki i rua ki te tekau ma rua nga tau o tau, taimaha iti iho i te toru tekau kirokaramu tinana, e tūtohu ana ki te tango i rima milligrams. Ko kotahi tango he hawhe papa ranei tenei. E kore e te horopeta rā nui tenei ahua. Ki te te taimaha o neke atu i te toru tekau kirokaramu, ka hei te taua rite mo ngā pakeke te inenga.

tuwhena rawa

Ki te kore koe e whakarongo ki te kupu whakatupato a te tango i te raau taero i roto i ngā rahinga nui, ka taea e meinga tohu i roto i ngā pakeke, ka e kia whakarārangitia i teie nei. Tenei tachycardia, pāhoahoa me te momoe. A tamariki nei taimaha he iti iho i te toru tekau kirokaramu, tuwhena rawa kia meinga palpitations, me tohu extrapyramidal.

Ki te uru te manawanui te tuwhena rawa, kia whakapā atu tonu koe i te tākuta. Ko reira tika hoki ki te tango i mehua ki te whakarite i nekehia te tarukino i te wahi gastrointestinal me heke te absorption i. mahi tenei e kukume emesis, lavage pekitīlia, me te whakamahi o te waro whakahohe. I roto i taea te kawea te take o te therapy symptomatic i whakatika te hiahia. Kia mahara te reira e te taonga kaha ko kore e taea te hīkarotia loratadine i te tinana i te tātari toto. Ano, i reira he kahore raraunga i runga i excretion o tenei huānga i roto i tātari peritoneal.

Ngā pāhekoheko ki ētahi atu taero

Ki te tono tatou i te "Klarotadin" i roto i te horopeta whakaora, i kitea pānga potentiating o inu waipiro. A ka whakanui i te tono o te tarukino ki taua paturopi rite "Cimetidine", "erythromycin" me "ketoconazole" te kukū i roto i te loratodina toto wē. e kore e tenei āhuatanga whakaatu hauora, me e kore pānga i runga i te hiko-.

He he taunakitanga e te inductors o microsomal piti hāora, e ngā waihā, phenytoin, barbiturates, rifampicin, ziksorin, pōuritanga tricyclic, phenylbutazone, ka taea e whakaiti i te whai huatanga o tenei tarukino.

Ara

Tūroro e mamae i te mahi waimaero ate, me e whai he hēnga o ōna whatukuhu (he tere iti iho i te toru tekau ml / min filtration glomerular), e kore e te horopeta tūtohutia tuatahi "Klarotadin" nui tekau milligrams (ko tetahi papa, ranei e rua koko whanganga o te tirikara tenei) i roto i te rua ra. Kore tatou e nehenehe e hoatu tenei tarukino ki tamariki, nei tau he iti iho i te rua nga tau.

kia te hunga katoa e tīmata tango tenei rongoā e mutu mo te roanga o nga wā maimoatanga i ahua o ngā mahi pea mōrearea e rapua e kukū tiketike, me ngā hohenga tere whakamātau tinana tetahi.

analogs

Ko reira tika ki te mea e kore tetahi o te ahua ko te tarukino "Klarotadin". Analogues i rua i roto i te raau taero kāinga, me te kawemai. Tika noa ke "hoa" he rongoā "Claritin". E tata ona āhuatanga te rite i o te tarukino runga ake-whakaaro "Klarotadin". Price - e te te rerekētanga matua. faaineineraa tāwāhi tino atu te utu. Ko te taua te utu kāinga, i runga i te whirihoranga rānei. Na, fao 7 RW. ka utu te reira e pā ana ki 100 moni pōkaitanga kia inea te aratau 10 x 3 -. āhua 270 moni, me 100 ml o te tirikara -. e pā ana ki 135 moni.

E kore e waiho e matou konei ki te kōrero e pā ana ki te mea ki te whakamahi i pai - "Klarotadin" ranei "Claritin". Ko te mea tūmataiti tenei, a ka whai ia koutou ki te whakatau hoki koe, te hoko hua kāinga cheap, kia hoatu hiahia ki ke atu te utu ranei. Ko te mea ia tapao e runga i nga tau tino pai-kï hua "Klarotadin". Analogs te kupu puta nga ra.

I roto i tetahi take, i mua i te tīmata koe tango enei taero me te ake na ki te whakaritea o ratou tamariki, kia mohio ki te kōrero ki tō tākuta. Tenei ka tiaki koutou i taea nunu'a kino e kia puta rite ki te hua o te ātete ki taero, te whakamahi hē o tona ranei tuwhena rawa. tonu kia mahara te reira e kia tū taua pānga te riri nui ki te hauora koutou, te hauora o koutou tamariki, me o koutou ora.