"Mesakol": tohutohu mō te whakamahi, ritenga tūturu

colitis ulcerative me te mate o Crohn e kitea i roto i te tūroro he tino onge. Ko, ahakoa tenei, i reira e maha raau taero e kua tikanga ki te hamani enei mate. Ko tētahi o ratou ko "Mesakol". Ka kia te aroaro tohutohu mō te whakamahi, puka, urupare, me te utu o nga moni i raro.

Te hanganga, te puka tuku, tākai me te whakaahuatanga

Drug "Mesakol", arotake o nei he huru rawa rangirua, haere i runga i te hoko rite te papa whero-parauri. He enteric-Uwhi ratou me te whai i te puka porohita me te lenticular.

Ko te taonga matua o te taputapu protrudes mesalazine (5-ASA). I tua atu ki reira o te tarukino ngā wae atu pērā i te witi māngaro, konupūmā pākawa dihydrate, talc e purea ana, microcrystalline cellulose, Titanium waikura, hypromellose 2208, silica colloid, povidone K90, konutai carboxymethyl māngaro, te methacrylic waikawa copolymer me methyl methacrylate, waikura rino whero, macrogol 6000 me dibutyl phthalate.

Papa "Mesakol" hangaia i roto i te takai konumohe, me ngā mōkihi pepa aua.

Pūtaiao

I mohio koe e ko te tarukino "Mesakol"? Tohutohu mō te whakamahi tohu e tenei kaihoko anti-inflammatory, paetata te pānga o nei i roto i te piro. Ko tēnei taonga o te medicament tika ki tona kaha ki te tautāwhi i te ariā o leukotrienes me prostaglandins, me neutrophil lipoxygenase.

kia mōhio hoki tatou e pōturi hekenga, phagocytosis me degranulation o neutrophils, me te immunoglobulin secretion i lymphocytes te tarukino whakaaro.

Aha te tahi atu āhuatanga i te rongoa "Mesakol", te utu o nei whakaaturia te raro nei? Mesalazine he mahi antimicrobial ki etahi cocci me Escherichia coli (i roto i te kopirua).

Pharmacokinetics

He aha e nga papa tawhā nekeneke tūturu "Mesakol"? Tohutohu mō te whakamahi kī e muri tukua whakahaere mesalazine te i te anga i muri e pā ana ki 115-165 meneti, a i muri i 170-230 meneti tareka papa.

tukua Nā kiriata tarukino whakaaro pani i runga i 60-80% te i roto i te kōpiro nui, me 15-30% - i roto i te whēkau iti. I roto i tenei take i te taonga kaha tae te tohanga nahanaha anake i roto i te nui o te 10% o te horopeta. Ko te tino iti Mesalazine kukū i roto i te wē.

Communication o te whakauru kaha ki pūmua wē ko 43%. Whakaaro he tarukino me ona metabolites ki te waiu uma.

Pākia mesalazine whakamana i roto i te whēkau, me te ate. Tenei hua N-acetyl-5-aminosalicylic waikawa.

Ko te hawhe-ora o 60-120 meneti (i runga i te horopeta rānei). tākihi rongoā whakaaturia me roto i te paru.

Tuhinga ki te farii i rongoā

E akono mate o te tarukino "Mesakol"? pūrongo arotake o tākuta e tenei taputapu tino tōtika faaite ake i roto i te mate o Crohn me colitis ulcerative.

Me kï reira e te whakamahia te medicament whakaaro mo te maimoatanga o te mate i faahitihia e kore anake engari ano mo te ārai o exacerbations.

Contraindications ki rongoā

Kaitūtohu "Mesakol" e kore e tūtohutia:

• i roto i te whewhe keté o te pūnaha kūnatu;
• mate toto;
• nui iti hoki tākihi;
• hemorrhagic diathesis;
• i roto i te tamarikitanga;
• nui waimaerotanga ate;
• hypersensitivity ki nga kai o te tarukino;
• kore o te kūhuka-6-Phosphate dehydrogenase.

Ki te tiaki nui te tarukino whakamahia i roto i te ngawari ki te whakaōrite pakeke o täkihi, me te āhua, me te ngawari iti hoki ate.

Papa "Mesakol": tohutohu mō te whakamahi

O nga moni i tangohia waha i muri noa i te kai.

I roto i exacerbation o mate e faaterehia te reira i roto i te nui o 400-800 mg (i.e., 1-2 papa) e toru ngā wā i te ra. kawea te therapy i roto hoki 9-12 wiki.

Hoki te ārai o exacerbations o te whakamahi tarukino i 400 mg toru nga wa o te ra. He tikanga te papa i roto i te puka o, inu wai noa.

Me pēhea te ki te hoatu tamariki i te tarukino "Mesakol"? Kānara, microclysters me te whakatārewatanga - i roto i tenei puka whakaaturia te te tarukino ki ngā tamariki.

tauhohe kino

Kia aroha mai, tango rongoā whakaaro tino maha ai ngā pānga taha. Ko ētahi o ēnei te whai ake:

• pericarditis, tachycardia, disorders cardiac āriponga, takawhita, uma mamae, hypotension, palpitations, hāhā o te manawa;
• whakapairuaki, heke hiahia, ruaki, hua i roto i transaminases ate, tokopā, stomatitis, korere, kakā, mamae puku, pancreatitis, mangai maroke;
• oliguria, proteinuria, crystalluria, hematuria, syndrome nephrotic, anuria;
• whanoke, ānini, moemoea, tinnitus, ohoroa, polyneuropathy, haehae, faaati, korekore;
• eosinophilia, thrombocytopenia, anemia (haemolytic, aplastic, megaloblastic ranei), agranulocytosis, anemia, hypoprothrombinemia;
• oligospermia, paruparu;
• ngoikore, photosensitivity, repe, whakaiti i te hanga o te inu roimata, syndrome lupus-rite, alopecia;
• rashes kiri, dermatitis, pruritus, bronchospasm, erythema.

Tohu o te tuwhena rawa

Tohu tuwhena rawa tikanga whakaaro protrude tikanga pērā i whakapairuaki, gastralgia, ruaki, sleepiness me te ngoikore. Hei whakakore i te whakaritea ratou lavage pekitīlia, laxatives me therapy symptomatic.

Hototahi ki ētahi atu hua

Drug "Mesakol" whakaiti i te pānga o "spironolactone" "Furosemide", "rifampicin" me sulfonamides. Reira whakatairanga hoki pānga hypoglycemic o pārōnaki sulfonylurea, te tāoke o methotrexate me corticosteroids ulzerogennosti.

Me kï reira ano hoki e pōturi te tarukino te absorption o cyanocobalamin me faarahi hoki te pānga o āpiha uricosuric (arā, blockers tubular secretion) me whakarei ake te pānga o anticoagulants.

tūtohutanga motuhake

• e kore e korere tupu i roto i te maimoatanga "Mesakolom" kia paingia tonu te pānga taha o te rongoā. kia waiho te huru taua te tohu o te mate e whāriki ana.
• I roto i te fariiraa, me auau kawea te taputapu i roto i whakamātautau toto me te mimi noa.
• Ki te ngaro te horopeta, kia tangohia e te whai i tetahi atu wa.
• I roto i te maimoatanga ki tenei rongoā me te mimi inu roimata o te manawanui kia tae i roto i te tae kōwhai-karaka.

Drug "Mesakol": ritenga me te utu

Whakakapia taea te rongoā mea kia e te tikanga pērā i "salazopiridazina", "5-ASA", "Tidokol" "Asacol", "Samezil", "salofalk", "Mesalazine", "Salozinal", "pentasil".

Kia pehea te nui Ko te "Mesakol" papa? Ko te utu o tenei tarukino ko 600-680 moni (50 papa).

arotake kiritaki

waiho tūroro te "Mesakol" teuteu ko arotake rawa whakauru. korerotia etahi o ratou e te raau tōtika akono mate intestinal. Etahi tautohe e he horihori enei pire. Ko te kupu, e nehenehe tatou e faaoti humarie e he pānga rerekē i runga i te tūroro rerekē "Mesakol".

Ko te drawback matua o tenei rongoā ko te maha nui o contraindications me tauhohe kino.