Paturopi Monoclonal. He aha te mea te reira me aha e ratou mo?

Paturopi (immunoglobulins) pūmua huaina Y-āhua. tango ratou wahi i roto i te tāutu me te excretion o wāhanga ke (antigens). kawea antibody i te taha o te pūnaha ārai mate i roto i te whakautu ki te antigen kătahi. Ia immunoglobulin taea ki te mohio ki a kōrero ki huānga motuhake manene.

Nā ki te meka e porotītiti te paturopi roto te bloodstream, e wātea ana ki nga wahi o te tinana e ratou. Ka herea e o te immunoglobulin ki te antigen kia aukati i te whanaketanga o ngā tukanga e whai wāhi ki te mate, arahi ki te whakangaromanga o te huānga ke ranei.

Ko te whakautu ārai o te tinana ki tetahi, ara nga tino ohie, ka karanga te wae ke te polyclonal. I roto i te mau parau te tahi atu, te pūnaha ārai mate hua (mahia) he plurality o immunoglobulins ki te mahi ki antigens rerekē.

paturopi Monoclonal e-pūtau iramate. Hoki ia ūnga pūtau taua (ūnga) tautuhitia te antigen mo te kite, me te here o te pūnaha ārai mate kua oti nei te whakawhanakehia he immunoglobulin motuhake, e mua pūtau.

synthesized te therapy Whakamahi ai i roto i te taiwhanga, nui atu i roto i te pūnaha ārai mate, he paturopi monoclonal. A, no te ingested, tīmata ratou tukanga whakahohenga o te tahi atu wāhanga o te pūnaha tiaki ki te whakangaro antigens motuhake. Ko te kupu, hei tauira, whakaurua ki roto ki te monoclonal antibody kaiao mo te maimoatanga o te mate pukupuku.

Ko te pūtau ki tou tuatahi e kua synthesized i roto i taiwhanga, ngā katoa o pūmua kiore. Tenei whakapataritari he raruraru, kaua nui. Ko te take i te "kiore" monoclonal paturopi te pūnaha ārai mate te tangata kite rite antigens - āhuatanga ke, a ko te kupu mahia he tauhohenga ki a ratou. e kore te tenei tika te tikanga te whanaketanga o te whakautu ārai. pūnaha Defense i roto i te tinana tīmata ki te whakangaro paturopi monoclonal i mua i taea e ratou ki a ia whai hua.

Ka rite ki te wā e haere, ka anga etahi o nga pūmua i roto i ngā pūtau kiore ki te whakakapi i ngā wāhanga pūmua tangata, ka karanga "chimeric". Ki te hua i roto i te ōwehenga o te āhuatanga o immunoglobulins tangata e (synthesized) i huaina "antibody monoclonal humanized".

Teuteu kei roto i enei wae, tirohia ki te tikanga o whakaora hāngai. I roto i te mau parau te tahi atu, e hangaia taero ki te mahi tika i runga i te pūtau, whakapataritari i te whanaketanga o ngā tukanga pathological. Ko reira maha tikanga pai atu i te regimens haumanu tikanga. I tua atu, he tokomaha o nga rongoa mua tikanga ki te hamani, no te tauira, sclerosis maha, mate pukupuku, kaikōiwi me ētahi atu pathologies he paitini, ka whai here i runga i toketaá katoa, e manakohia ana hoki whakahaere ki te manawanui.

I roto i te rongoa tino rongonui kia paturopi monoclonal kia tuhia taputapu pērā i "MabThera", "Rituxan" (whakamahia i roto i te lymphoma kore-Hodgkin o), 'Herceptin' (whakamahia hoki pukupuku uma).

I te rongoā he tūmanako tiketike o synthesizing hangarau o paturopi monoclonal. Heoi, i reira e te tahi mau fakangatangata. Ko te kupu, immunoglobulins synthesized he rāpoi nui rawa. e kore e tukua te reira ki a ratou tomo hohonu ki te kopa ranei ki te pūtau. e kore e ratou te tikanga mo te waha (waha) whakahaere. Ano, ki te whakatutuki i te pānga e hiahiatia ana o te kukū o enei paturopi kore e nui rima ki te tekau mano nga wa te kukū o te ūnga antigen. Whakawhanake immunoglobulins synthesized whakamana anake i roto i ngā ahurea pūtau, e i roto i te tahuri ratou production tino utu hanga.