"Quinidine": tohutohu mō te whakamahi, hanganga, whakaahuatanga me arotake

He aha te mahi e hiahia ana matou he taputapu pērā i "quinidine"? Tohutohu mō te whakamahi, utu, me arotake e te aroaro te whakarite o te tarukino i raro. Ka ako ano hoki koe ki ta nga āhuatanga pharmacological āhuatanga o te tarukino, ahakoa ko reira te taha mahi o te huru, me mehemea he ia tetahi here mō te whakamahi.

Te hanganga, te āhua, whakaahuatanga

I roto i te aha puka kamupene ho'oraa kia tarukino "quinidine"? Tohutohu mō te Whakamahi, piri ki tenei tikanga, ko e taea te hokona te reira i roto i te puka o papa papatahi, me te a tawhio. E ratou he pānga roa me te kiriata-Uwhi.

Ko te whakauru matua o tenei rongoā ko quinidine pūkawa. Tohutohu, e kore e hoatu e whakaahuatanga hua tetahi mōhiohio i runga i matū atu.

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He aha e nga pire "quinidine"? Tohutohu mō te whakamahi, whakaahuatanga, kua korerotia arotake e ko te reira he rongoa mo Class IA arrhythmia. He mea e taea ki te pōturi te waka o katote i roto i takere Na taiepa pūtau nohopuku o cardiomyocytes me te whakaiti i te rohe depolarization tere, me te whakapiki ake i te roanga o te pūmanawa mahi me whakangutungutu (whai hua) roa o te wā.

Fariiraa o te medicament attenuates excitability myocardial, pōturi automaticity me AV-āriponga i te kōpuku, poraka peka paihere, Atrial me ētahi atu hanganga. tikanga whakaaro hoki he pānga vagolytic faaite pānga m-anticholinergic, te whakaiti i te mahi (contractility) o te uaua ngakau, me te ai he whakaiti i roto i te pēhanga toto.

āhuatanga o te tarukino

He aha te mea faahiahia ko te rongoa rite "quinidine"? Tohutohu mō te whakamahi tuhipoka e taea whai reira he pānga kino inotropic. puta tenei rite ki te hua o te whakapōturinga o te tukanga faafariuraa pūngao ā i roto i te pungaraungao. Ki te whakaaro ki te āhuatanga antiarrhythmic o te raau taero, e pā ana ratou ki te aroaro o ngā rōpū amide i roto i te hanganga rāpoi ngota o te taonga kaha.

E ai ki nga tohunga, kei te tino heke te rōpū o tenei medicament excitation me whakatö tere, e pā nei te ki te rongo o te wāhanga tarukino hohe ki te tukanga o te depolarization.

Pehi receptors m-cholinergic, whakaaro whakaongaonga te raau taero AV-kawenga. I pota haumanu whakaaturia reira āhuatanga hypotensive e pā ana ki te whakaiti i reo uaua piringa me pera, me te he pānga kino inotropic.

E kore e taea e tatou te mea e taea ki te whakaatu pānga irritating rohe tenei tarukino ko. Reira He āhuatanga analgesic me antipyretic e pā ana ki te pānga depressing i runga i te roro hoki.

Ko te āhuatanga pharmacokinetic o

Whenumi ahakoa te taua whakauru kaha o te tarukino rite quinidine pūkawa? Tohutohu mō te whakamahi ngā taua fariiraa o te kaihoko-waha whakatairanga tona kukū nui i roto i te toto i muri i 95 meneti.

Tauhohenga o tenei ki te pūmua medicament ko e pā ana ki 77-80%. puta tōna biotransformation i roto i te ate. Heoi, kua hanga e etahi pärönaki mahi cardiotonic.

Ko te hawhe-ora o tenei taputapu ko āhua 7 haora. I whakatahia te reira i roto i te whatukuhu. Na roto i te acidification o piki medicament mimi excretion me ka tona alkalization - leva.

Mai te mea i whakaritea te?

He aha e nga tohu mo te whakamahi o te raau taero e "quinidine"? kī Tohutohu mō te Whakamahi e te anake tika ai te whakaaro o te raau taero i roto i te wā e whai ake nei:

• i Atrial tachycardia, AV-tachycardias, extrasystoles ventricular me supraventricular, patua o fibrillation Atrial me te kaka;
• ki te ārai i whakaeke o tachycardia (supraventricular me ventricular), me ventricular fibrillation;
• i muri i te cardioversion ki te pupuri pakohu manawataki.

Ūhia ki te whakamahi

He aha e te huru o te manawanui e riria te whakamahi o te rongoā "quinidine"? Tohutohu mō te whakamahi (te utu o nga rongoa tabulahia i raro nei) pūrongo o contraindications o te raau taero, pērā i:

• ru cardiogenic;
• AV-poraka (tuarua tuatoru ranei tohu);
• te purapura thrombocytopenic, i whakawhanakehia i muri i tango i te raau taero;
• mate (nui) āriponga intraventricular;
• paihere poraka peka;
• haurangi digitalis, haere tahi nei i abnormalities āriponga;
• he urupare kë ki te tarukino;
• gravis myasthenia.

Medicament "quinidine": tohutohu mō te whakamahi

Manakohia kia te taputapu roto 60 meneti i mua i muri i 125 meneti i muri i kai ki te karaihe tonu o te wai ranei. Ki te hiahia koe ki te whakaiti i te pānga tumu o te raau taero i runga i te membrane mucous o te wahi kūnatu, he mea e tika ana ki te whakakapi i te wai ki te waiu.

e kore e tūtohu tarukino auroa ki te whakahoki ake kuru ranei.

whakaaro te inenga paerewa te 200-300 papa mg wha nga wa he ra. Ki te tachycardia supraventricular (ki paroxysms) Kei te nui haere tenei nui ki te 400-600 mg katoa 3 haora i mua i oti te tauturu o te paroxysm. I roto i te fibrillation Atrial, medicament te fariiraa 200 mg katoa 2 chasa (5-8 wa ia ra). Ai te horopeta tiaki ko 200-300 mg wha nga wa he ra.

regimens Alternative: 400 mg (ki te kore i tāmau te whakaeke, te mg 200) nga 60 meneti noa oti whakamutunga o te whawhai, ranei ki te whakatutuki i te katoa inenga o 1 g

I roto i te ngaro o ngā pānga taha i muri i te horopeta tuatahi i roto i te fariiraa muri o te nui o te medicament ki kia nui haere ki te 600 mg. Ka mau te raau taero i roto i te i te taikaha o te 4 karamu ia ra rāhuitia te.

Dosing mō ngā tamariki

I roto i te horopeta o rongoā whakaritea ki ngā tamariki "Dyuruls quinidine"? Tohutohu mō te whakamahi, pediatricians whakawākanga kī e te inenga paerewa o tenei kaihoko mō ngā pēpi, ko te 6 mg / kg 5 wā ia ra. kia waiho kaitūtohu anake hei tākuta mātanga, tino i runga i te whakaaturanga.

Hohenga i-pūāhua

He aha nunu'a kino kia puta i muri i te whakamahi o te tarukino "quinidine Durules"? Tohutohu mō te whakamahi, whakamārama o tenei tarukino kōrero te tauhohe kino e whai ake nei:

• asthenia, whakawhänui te wā QRS, gravis myasthenia;
• mōwaho ngā patu ventricular, rongo mate;
• mate o te hiahia, fibrillation ventricular, Thrombosis matua, te pēhanga toto raro;
• raruraru ataata, ventricular tachycardia, paroxysmal, tinnitus,
• asystole;
• whakapairuaki, pakohu bradycardia, kakā, mamae puku, te whakama;
• gastralgia, ānini, ruaki, thrombocytopenia, korere, whanoke, anemia hemolytic;
• kirika, syndrome lupus-rite, ohorere kiri.

take o te tuwhena rawa

He aha e nga tohu o te tuwhena rawa e taea meinga rongoā "Dyuruls quinidine"? Tohutohu, kōrero i nga tohunga kōrero e pā ana ki taua faaiteraa rite tinnitus, korekore o te mahi cardiac, te maturuturunga iho i roto i te pēhanga toto, whanoke, kaka Atrial, diplopia, quinidine ru, rongo mate.

Hei whakakore i taua āhua pāngia whakaritea lavage pekitīlia, supply hāora, māngai hypertensive, kaiwhakahaere, tātari toto me te ventilator.

taunekeneke tarukino

Me pēhea te ki te hamani pähekoheko te tarukino ki te taonga rite quinine? korerotia Tohutohu mō te whakamahi (e nga arotake utu o medicament kia aroaro i te mutunga o te tuhinga) e faarahi tenei huinga i te tāoke o rua.

Ano, taunekeneke "quinidine" pire ki te rongoā e whai ake nei:

• taero Antiarrhythmic whakarei mahi cardiodepressive.
• Anticholinesterase taero me rongoā whakarei nga pānga kalisodergaszczye "Quinidine".
• taero Anticonvulsant whakaiti taumata toto o "Quinidine" ka whakaiti i tona whai huatanga e tika ana ki te whakaongaonga o tona pākia.
• Laxatives whakaiti te whai huatanga me te kukū o te tarukino i roto i te toto i raro i te arotake.
• Rongoā alkalising te mimi, faarahi te mōrea o tauhohe paitini.
• Drugs "amiloride" me "Amiodarone" whakaiti i te whai huatanga o "Quinidine" ka roa ona QT āputa, aua.
• waikawa ahipirini toro toto, petechiae me whakatairanga toto i te whekau kūnatu.
• Medicaments "fafati" me "Verapamil" - whakarei pānga anticoagulant o te auau heke tuatahi, me te tuarua o te excretion.
• Drug "Haloperidol" - faarahi i tona ihirangi i roto i te toto me te whakanuia ana te mōrea o tauhohe kino.
• Drugs "Hydroxyzine" me "dextromethorphan" - faarahi te tūponotanga o te arrhythmia nui i te fariiraa o te tuatahi, me te tuarua i roto i te toto.

mōhiohio motuhake

Ki te whakaahuatia tūpato motuhake rongoā tūtohutia hoki te kore te ngakau ma'i wāhanga 2-3, tachyarrhythmia (ventricular) ki te wā elongation QT, pakohu kōpuku, AV-pā 1 tohu, huangō, hyperthyroidism, hypotension, mate hopuhopu whakapeka, emphysema , koki-katinga papahewa, hypokalemia, kore ate, thrombocytopenia, repeure hyperplasia, ma'i täkihi, hohipera, hapūtanga me te psoriasis.

Iwi ki myocarditis me ētahi atu mate myocardial ka fariiraa i "Quinidine" hiahiatia mana hauora wā te. I mua i te maimoatanga, me hanga te manawanui he ako o te tohu o hypokalemia me kore o te ngakau.

hiahiatia ana te therapy te ki te aroturuki tonu nga raraunga ECG o te toto piringa me hemodynamics.

tikanga e rite, utu

Kua whakaaro analogues Drug te rota. huanga Tohunga ki a ratou nga tikanga e whai ake nei: "Kinidin Durules", "Bretilat", "procainamide", "Etatsizin" "Lidocaine", "Amiokordin", "Propanorm", "Amiodarone" "Verapamil", "Propranolol", "Ritmonorm ".

Ko nga utu o taua rongoā rite "quinidine" me "quinidine Durules", nga tangata o to matou whenua, he unknown ratou e tika ana ki te meka e kore enei taero hokona i roto i Russia. Heoi, e taea te hokona ratou i roto i Ukraine. Ko te utu o te raau taero i roto i te whenua, ko te pā ana ki 540, me te 670-679 hryvnia, aua, e te mea rite ki te 1380, me te 1760-1780 moni.

Reviews

He aha te iwi mea e pā ana ki te tākuta medicament whakaaro me ētahi atu ngaio? E ai ki a ratou, io tenei taputapu ki te kia tino whai hua tarukino antiarrhythmic, i te mea pai, me te nohopuku nui ki te hamani mate pērā i ventricular me tachycardia supraventricular. Heoi, kia tuhia te reira e te rapu mō "quinidine" pire i roto i pharmacies Russian kore e taea. Ko e tika ana ki te meka i kapea ki tenei rongoā i tohanga noa, me te te kore whakamahia i roto i ngā hōhipera tenei. Doctors whakamārama tenei āhuatanga i te meka e reira e haumaru me te ake whai hua me te ritenga utu i roto i te mākete ho'oraa, Kei te mātātoa i whakamahia mo te taua tohu. I roto i tenei take, tohunga te mea e haere tonu quinidine pūkawa ki te whakamahi rite te wāhanga o matū multicomponent i roto i maha taero anti-arrhythmic.