Ati huna - mate o Huntington

pukapuka tohutoro Medical hoatu he whakamāramatanga rawa matatini o te mate, e kiia nei ko te mate o Huntington. I roto i te tikanga ki te mahino te takenga me ngā āhuatanga o tenei mate e wehingia ana, he mea e tika ana ki te matau i te tuatahi te mea whakamahia ia wāhanga e i roto i tona whakamāramatanga.

whakaaro te mate te ki kia tuku, autosomal tino. Tenei te tikanga e he ira, me te riro i rānei matua te mate, he i te iti rawa kia kotahi ira mutated. Ko te pā i roto i te mau tamaroa e te mau tamahine ōrite.

mate o Huntington - he mate o ma'i ahu whakamua. E kore te tukinotia reira, āta whakawhanake reira, te whakanui ake tonu tohu, ētahi wā neke i roto i te wā whakapeka. Kei te haere tahi tonu te mate e disorders hinengaro, whakararuraru extrapyramidal (disorders kaupapa).

Kua te pathogenesis o tenei mate kua ako rawa painga. Heoi, kua mohiotia taua mea e i roto i tūroro tangata ko maha he kaimahi o o Kapa (waikawa aminobutyric, i te mea te neurotransmitter inhibitory tino nui) i roto i te pūtau roro. Na, i roto i nga pūtau o te nigra substantia te tikanga faarahi te nui o rino, i reira e koi disorders o te pākia dopamine. Ētahi tohunga whakapono e te mate mate o Huntington meinga e tawharara mekameka o waikawa amino. Nā tēnei synthesized "he" pūmua whakararuraru i te tukanga matüora i roto i te roro.

Kei te pai te whakapumautia te reira e te tūponotanga o ia i te tamaiti ki te mate i roto i te ira pāpāho whānau pakaru ko 1: 1 ahakoa o te sex o te tamaiti.

Tohu o te chorea o Huntington

mate o Huntington nuinga riro kitea ki te 30 tau (i ētahi wā i muri mai). Tuatahi, i reira ko te mate hinengaro: he whāiti o te mahara, "jam" i runga i tetahi whakaaro. ngaro te iwi te kaha ki te tātari i te āhuatanga, me te whakatau.

Āta whakawhanake enei disorders ki dementia matatau. Te manawanui hinengaro tere mauriora, tuukino te maramarama riro wheako. Āta mara te tuakiri o te manawanui.

I roto i te whakarara, whakawhanake disorders hyperkinetic. Tūroro ki te tātaritanga o "mate o Huntington" oke ai timata ki te hanga i te rota o nekehanga iti, ko te kupu ngaro te kaha ki te whakaputa i ngā mahi ohie. Hei tauira, e haere ana haere tahi grimacing, poipoia ringa, me te m. P.

e kore ko te taua mate o Huntington. I te tahi taime, ina koa i roto i te tīmatanga o nga wāhanga, kia puai tūroro ki te pehi ara he hyperkinesis kaha, a i roto i te tahi atu te wā e taea te whakahuatia te reira rawa painga. Kei te haere tahi tonu te mate tupu, engari kia kia rerekē te tohu o tona pakeke. I te tahi taime tūroro, i te noa'tu o te kinonga ta'etukú, kia mau ratou whaiaro matua, a ētahi wā mate ano ia rawa hohoro. He aha pūkete hoki taua āhuatanga, e kore te ano whakapumautia te rongoā.

mate o Huntington. Tātaritanga me te maimoatanga

Hoki te tātaritanga, me mamae tūroro Tirohia te, MRI. Ko te tikanga e rēhita enei rangahau atrophy o te uho kaka me te huringa i roto i tona mahi hiko, i reira he pera-ka karanga te nukunga me te thalamus.

Hoki te tauākī o te tātaritanga, te korenga i hoki kaiwhakaako te inu cerebrospinal, ako te hītori o te mate i roto i te utuafare. I teie mahana atu me te ake tohaina tikanga mo te tātaritanga preclinical mō ngā whānau e te hunga i roto i te rōpū mōrea. takoto te reira i roto i te tūtohutanga o lymphocytes ki ako X-hihi. Tamariki whanau i roto i te mau utuafare i reira i reira ko te kawe mate, kia waiho i roto i te pūkete hauora.

mate o Huntington e kore e mahu. I roto i te tikanga ki te whakahaere i te huru o te manawanui e taea te whakaritea ki complexes o triftazine, reserpine me ētahi atu te raveraa ra dopamine me tranquilizers.