Ko te tarukino "Ofloxacin": mua manawanui. Tohutohu mō te whakamahi o te rongoā paturopi "Ofloxacin"

Te faaineineraa "Ofloxacin" whakawākanga tūroro e te nuinga pai, tohu te kaihoko antimicrobial i te rōpū o fluoroquinolones hihinga o mahi whanui. pānga te tarukino te gyrase DNA - kongakonga kitakita, whakarato supercoiling me reira te pūmautanga o te huakita DNA (rite ki te hua o te destabilization o mate whenu te DNA).

pharmacodynamics

Tikanga "Ofloxacin" - he paturopi whai hua ki te whakapai kanohi ki microorganisms e hua beta-lactamase, me te mycobacteria mohiotia nohopuku-tipu. Ki ngā rongoā e tairongo, te nuinga o huakita Gram-kino, tae atu ki ngā microorganisms e te hunga ātete ki te methicillin me ētahi atu paturopi. E āhuatanga Streptococci, enterococci, me Mycobacterium kohi i susceptibility iu ki te tarukino "Ofloxacin". Reviews o rata tohu e i roto i te maimoatanga o te mate anaerobic meinga e peptostreptokokki, peptokokki me ētahi atu anaerobes, he maha koretake te tarukino.

Pharmacokinetics

Ki runga ki te fariiraa i te medicament ki te absorption he oti (95 ōrau) me te nohopuku. Bioavailability - neke atu i te 96 ōrau. Whanaungatanga ki pūmua wē - 25 ōrau. I muri i tetahi ki te e rua haora i muri i whakahaere-waha o te kukū rawa i uru. Ko horopeta-ti'aturi: te whakamahi kotahi o e rua rau, wha ranei e ono rau milligrams o kukū tarukino i aua 2.5, 5 6.9 ranei UG / ml.

Ka taea e kohi kai pā te absorption o te taha o te āta, engari kahore nui pānga i runga i bioavailability. Te faaineineraa "Ofloxacin" - he rongoā paturopi he rōrahi nui o tohatoha (kotahi rau mehua), kia e te faaineineraa whakahaere he tata ô i nui tonu noa ki te pūtau. Ko nga nohanga teitei i roto i te kopa, fluids tinana me okana: i roto i te pūtau (macrophages kauae, leukocytes), kiko ngohengohe, kiri, wheua, pūnaha romahā, kōhao papatoiake, me te puku, huware, secretions prostatic, mimi, ate. ô i te puna medicament te placental me toto-roro arai, kua huna ana i te waiu, uma, a tomo inu cerebrospinal i te kiriuhi roro kore-matia, me te matia (14 ki te 60 ōrau).

metabolized Mō 5 ōrau o te raau taero i roto i te ate ki te hanga i dimetilofloksatsina me N-waikura o ofloxacin. Ahakoa o te horopeta hawhe-ora ko waenganui i wha me te hawhe ki te whitu haora. Putanga tarukino tonu i roto i te nui o 75-90 ōrau o te whatukuhu, i roto i te nui o 4 ōrau - i roto i te ate. Iti iho i te 20 ōrau o te whakawātea extrarenal. I muri i te horopeta kotahi o e rua rau milligrams o kaihoko he detectable i roto i te mimi mo 20-24 haora. I roto i te take o te excretion ate tākihi ranei kia pakanga ai. A, no te nekehia atu tātari e 10 ki te 30 ōrau o te rongoā.

Tuhinga hoki

I roto i te mate hopuhopu, me te inflammatory meinga e ngā microorganisms, whakaaturia tono medicament "Ofloxacin". Kua korerotia Reviews e he reira rawa pai mō mate romahā wahi (kakā, Bronchitis), i runga wahi romahā (pāpāho otitis, pakohu kakā, laryngitis, pharyngitis). Vahe ki tarukino i roto i ngohengohe pāpaka kiko, hononga, wheua, kiri, wahi biliary, mimi (urethritis, cystitis), tākihi (pyelonephritis), kōhao puku, taihemahema (orchitis, colpitis, epididymitis), whekau papatoiake (salpingitis, prostatitis, cervicitis, endometritis, oophoritis, ngā tawhā).

Hoki tarukino whai hua mō te ureaplasmosis, chlamydia, gonorrhea. Whakamahia ai hoki te ārai o mate i roto i te tūroro ki te disorders o te mana ārai (tae atu i te neutropenia).

Ko te puka inenga. hanganga

Ko te tuku o te medicament i te puka o papa kiriata-pani biconvex hanga a tawhio ma ranei tata ma Uwhi. Ko te ripeka motu e rua ngā papa kite, kua he kauruku kowhai tetahi o nei. mahi wae Hohe rite ofloxacin. Kotahi papa i roto i roto i te papatipu o te 200 400 e aore mg. He primelloza (croscarmellose konutai) kai iti, microcrystalline cellulose, Aerosil (colloidal hāorarua silicon), silica Titania, povidone, methylcellulose hydroxypropyl (hypromellose), talc, konupora stearate, polyethylene glycol 4000 (macrogol). He painga nui o te tarukino "Ofloxacin" - utu. Papa kei roto 200 mg o taonga kaha ko te toharite o 16-20 moni ia 10 mongamonga, me te hunga e roto i 400 milligrams ofloxacin, ka utu e pā ana ki 50-55 moni ia 10 nga wahi.

"Ofloxacin" rongoā. Tohutohu mō te whakamahi

kia inu Papa i mua i muri i te kai ranei. Me horomia ratou katoa, kahore ngaungau, a inu wai i roto i ngā rahinga iti. kia whiriwhiri te inenga takitahi i runga i te pakeke o te mate, te localization o te mate, e tu'unga whānui o te manawanui, tākihi mahi, ate, me te huakita tūtohutanga rānei.

Ka rite ki te tikanga, "ofloxacin" Kei te hanga te maimoatanga o mo e whitu ki te tekau nga ra. Pakeke ia whakaritea te horomanga o rau e rua, e ono rau milligrams rua he ra. kia kia nui haere te horopeta ki e waru milligrams i te take o te mate nui, ranei, ki te he taumaha te manawanui. Ka taea te tango te horopeta o wha milligrams i kotahi, arā i roto i te ata.

Tūroro ki taumahi waimaero tākihi kore kotahi e taea te tango atu i te rua rau milligrams o tarukino, te horopeta mōrahi ia i roto i te waimaerotanga ate - wha rau milligrams. I muri i te ngaro o ngā tohu, me te māori o te pāmahana, ara mo te rua ranei e toru nga ra e haere tonu therapy.

pānga te taha. mua

Ehara i tūroro katoa te tarukino "Ofloxacin" nohotahi pai. Reviews o etahi iwi i roto i ngā mōhiohio e te raau taero ai ānini, whakapairuaki, ruaki, korere, tremors, te kōpā o pito. I runga i te wahi o te pūnaha kūnatu kia whakawhanake rite mamae puku, gastralgia, bloating, jaundice cholestatic, anorexia, hyperbilirubinemia, enterocolitis pseudomembranous, me te pūnaha io - kore o kaupapa, cramps, moe kaha, tauhohe psychotic, rōpū,, manukanuka, whakama, phobias, moemoea, korekore.

I tua atu, i reira ko te mōrea o maumaui o te pūnaha nekeneke (arthralgia, tendonitis, myalgias), rongo (disorders reka, kite tae, rongo, toenga, kakara), pūnaha iaia me te ngakau (whakaiti i roto i te pēhanga toto, tachycardia), te kiri (dermatitis, wāhi toto, ponana papular), o te hematopoiesis (thrombocytopenia, anemia, leukopenia). I muri i te fariiraa i "Ofloxacin" tarukino (arotake whakau tenei), i roto i ētahi wā puta reira oranga kiri, bronchospasm, urticaria.

contraindications

Te fariiraa i medicament ātete riria ofloxacin me ētahi atu pārōnaki fluoroquinolone, i roto i te take o te hē o te kūhuka-6-Phosphate dehydrogenase, haurangi, pāpaka o nga tendons, whakaiti ärai paepae. I tua atu, e kore koutou e taea e te tango i te tarukino "Ofloxacin" wahine hapu, me te lactating, tamariki i raro i te tau o waru. Ki te whakaritea faaineineraa tupato kei hoki disorders circulatory i roto i te roro, atherosclerosis iaia kaka, täkihi i ma'i CNS pāpaka āhua organic.

Medicament "Ofloxacin" i te ureaplasma. Reviews

Ko te mea matua ko te e mea te iwi, te whakamahi i te hua - te reira tona pānga tere. pūrongo tūroro e he kite te hua kua i te toru ranei, te wha o nga ra. Ko te mea e tika ana ki te whakatupato e kore e tenei tikanga i te tīmatanga o te rongoa. Ko te hunga tūroro e kua mutu ki te inu papa, kahore haere i roto i te akoranga tonu, ka ite ano tohu ureaplasmosis, no te mea kahore i tino whakakorea nga huakita.

Ara

A, no te kakā whakapataritari i pneumococcus, te raau taero hua. Ano, e kore e tohua ai mo te maimoatanga o te tonsillitis whakapeka. He mea tika ki te aukati i te tarukino, ki te i runga i te whakamārama o tona whakauru wheako i te tauhohenga pāwera, te whakararuraru CNS, colitis pseudomembranous. Women tono tikanga "Ofloxacin", e kore e tūtohu ana ki te whakamahi i tampons, no te mea i roto i tenei take ki reira ko te kaha ake te tūpono o te whakawhanake piopio.