Konutai nitroprusside: tohutohu mō te whakamahi

He maha raau taero e whai pānga hypotensive. Drugs e iti pēhanga toto, Kei te nuinga o te wā e whakamahia ana i roto i te matatini me te ngā (1-2 wa ia ra). Ko te kupu peratia takawhita. I roto i ētahi wā, ritenga ki taero whakaiti pēhanga toto e kore e tono. Na ka tono rongoā kaha pērā i te otinga 'o konutai nitroprusside. " e kore te tenei tarukino whakamahia pūnahanaha me kahore te hiahia nui. Ehara i te mea he rongoā o kōwhiringa mō te maimoatanga o te takawhita me kore ngakau ma'i. Kei te whakamahia te reira i anake i roto i te wā o te whawhati tata, ka kore e urupare tinana o te tangata ki ētahi atu raau taero e whakaiti pēhanga toto (Diuretics, ACE inhibitors). He otinga 'o konutai nitroprusside "kore e taea te whakahaere anake, kahore te whakahaunga.

He aha te pānga o te raau taero e runga i te tinana?

Te faaineineraa "nitroprusside Konutai" (tātai - C ₅ repo ₆ Na ₂ E) e pā ana ki te rōpū o vasodilators piringa. Kei te reira i te tae whero pouri taonga i roto i te puka o tioata ranei paura. Ko diluted tona faaineineraa ki te wai, me te whakamahia i roto i te puka wai. Nā ki te meka i reira ko te rōpū nitroso, te whakamahi o te raau taero ai vasodilation i te hanganga o te taonga. Tenei tupu e whai ake: tenei pūhui matū ka ingested te tahuri ki waikura nitric me whakahohetia te paru - cyclase guanylate. Ai whakarei hanganga o cGMP e whangai ana ki te whakaemi i roto i te uaua maeneene iaia me ai tona whakangā. Nä, ko te medicament "nitroprusside Konutai" whakarato te pānga e whai ake nei me te arterio venodilatiruyuschy me hypotensive. Na roto i tenei mahi o te pūnaha iaia te whiwhi pai hohoro. I tua atu, mahi te otinga rite ki te momo o glycosides cardiac, i.e. whakaiti reira tono hāora myocardial. tutuki ana tēnei pānga e mua- me afterload heke.

Tuhinga medicament

kia hounga'ia reira e whakamahia te raau e anake i roto i te wā whawhati tata o mate taumaha, me te ātete o te rauropi ki ētahi atu rōpū o medicaments. ka karanga te Tuhinga mō te whakamahi o te raau taero:

1. kore ngakau whakapeka. I roto i ngā whai tatou i roto i te ngakau te whanaketanga o te edema pūkahukahu (huangō cardiac). Ko te tere ārai tenei āhua ki kahore he pānga o Diuretics te tarukino.
2. kore ngakau ma'i, nui. Ko te atamira whakamutunga o te kore ngakau ma'i (2b, 3) e kore e whakautu tonu ki te maimoatanga. Na reira, ka whakahau ātete ki ētahi atu raau taero, me te huru fifi o te manawanui vasodilators piringa.
3. Whakapeka syndrome coronary. I roto i ētahi wā, e whakamahia ana te raau taero i roto i infarction myocardial, ki te whakaiti i te pēhanga i roto i te oko toto o te ngakau, me te ki te karo i te whanaketanga o te ru cardiogenic.
4. A tātau ki te maimoatanga tuku iho o te takawhita. Ka taea te whakamahi Vasodilators i pheochromocytoma, mōrearea paroxysmal, me te te whanaketanga o pōauautanga nui meinga e te hua koi i roto i te pēhanga toto (patu, disorders psychogenic, whakaeke ngakau).
5. paihana Ergot. Tenei te tipu ko te vasospasm koi, e kia haaparuparu mā medicament "konutai nitroprusside." kia pai kia matau tohutohu mō te whakamahi i roto i fakahū mōkihi e taote "waka tūroro" me te whakaora.

Contraindications me ngā pānga taha

e kore e whakamahi i te tarukino i roto i hemorrhagic patu, me te i muri i te reira. Kei te contraindicated reira mo te iwi e mate ana i te mate tākihi ma'i me hypothyroidism. Kei te kore hoki tūtohutia reira mo tangata ki te pēhanga intracranial nui haere. Kei te araia te whakamahi o te rongoā mō ngā tamariki, wahine hapu me te iwi i roto i te tau tawhito. Ko tētahi atu contraindication he kātaki'i kaihoko kaha ki te whanaketanga o mate pāwera.

I roto i te pānga taha i te whakamahi o "konutai nitroprusside" teuteu ko ki te whakarato i tētahi hekenga koi i roto i te pēhanga toto (i roto i tenei take, he mea e tika ana ki te mutu tonu whakahaere), nui haere auau ngakau, whanoke, whakapairuaki, me te ngoikore whānui.

tauhohenga matū ki te konutai nitroprusside

I tua atu ki te whakarato i te pānga haumanu o konutai nitroprusside substance whakamahia i roto i te tauhohe matū. Ki te konatunatua reira ki te tinana ketone (hauwaiwaro) ka whakanohoia i roto i te taiao kawakore, ka taea e kite koe i te huringa mīharo i roto i te tae o te pūhui. Hoki taua panoni te whakamahi i 4 korere. I whakanohoia ia tetahi anake taonga - nitroprusside, hauwaiwaro, alkali, waikawa ahetiki konutai. I roto i te take tuatahi ka tahuri te otinga hua hue kanapa karaka-whero. Next, diluted tenei pūhui te ki waikawameha ahetiki. ke ano Tae, tenei wa riro te wai pouri whero papura ranei.

Te faaineineraa "nitroprusside Konutai": tohutohu mō te whakamahi

Ki te tomo i te tarukino, he mea e tika ana ki te whiwhi te uru rō-uaua. Tonu i mua i te tīmatanga o te whaowhia tarukino, kia diluted reira i roto i te 5% otinga kūhuka. Hoki tenei whakaaro, 1 pounamu o te tarukino i roto i te pūwero me diluted ki 5 ml o te wai. I patia te ranunga hua ki te pounamu ki te 5% te kūhuka ki te tareka anō. I muri i taua, tangohia ake te inenga e hiahiatia ana. pae te reira i 0.3 ki te 8 g ia 1 kg o taimaha tinana. Kei te hanga te whaowhia i roto i te pūnaha. kia tīmata te reira ki te horopeta iti, me te āta whakanui i te reira i raro i te mana o nga tohu faufaa (BP, auau ngakau, he pini). Ko reira tika hoki ki te whakaturia te auau e whaowhia manakohia rite ki te 2.5-3 mg / kg i roto i te 1 meneti. Tei te inenga i runga i te wa o te whakahaere tarukino. Me aroturuki whaowhia roa te taumata o te medicament cyanide-kei roto i roto i "nitroprusside Konutai". kia mārama hei maharatanga tohutohu mō te whakamahi o te raau taero.

Ngā pāhekoheko ki ētahi atu taero

E kore matou e tūtohu te whakamahi o te raau taero, me ētahi atu āpiha antihypertensive, rite te whanaketanga ka taea o te kāwanatanga o te ru. Me mōhio e te whakamahi o te whakawhānau ā-waha te whakaiti i te whai huatanga o te tarukino. A, no te ngā ki te medicament tarukino "Dobutamine" mō tohu faufaa o te manawanui me te āta aroturuki (pēhanga iti pea, wedging i roto i te oko pūkahukahu me te nui haere rōrahi cardiac).