Lactulose: tohutohu mō te whakamahi

Lactulose Ko te stereoisomer reihuka āwenewene synthesized - huka waiu. Ka rite ki a ia, Kei te rāpoi ngota lactulose toenga o ngā rāpoi ngota o te huahuka me galactose, heoi kihai i kitea te āhua o te taonga.

Lactulose, paura ma wairewa, ka whiwhi tuatahi i reihuka i roto i 1929, engari e tuwhera ona āhuatanga rongoa nui i muri. I te tuatahi whakaahuatia anake ona hua i roto i te toru tekau nga tau. I tēnei wā, hua e hāngai ana i runga i tenei taonga, ko tetahi o te whai hua tino me rongonui laxatives.

Lactulose, tohutohu hoki te whakamahi o nei te whakamārama taipitopito o ona āhuatanga, no ki te piha haapiiraa o pera-ka karanga prebiotics - matū e tomo te tinana i roto i te kai, otiia kihai i whenumi a kihai i raro ki te nakunaku. takoto ratou uara i roto i te meka e whakaongaonga ratou te tupu whēkau o microflora painga, tango wahi i roto i te nakunaku. I roto i tenei - i te rerekētanga matua i waenganui i prebiotics ki te nuinga o laxatives, whakarato i te mahi e tika ana e tika ana ki te pānga i runga i nga uaua maeneene o te whēkau. Amplification motility intestinal lactulose (tono Kaiwhakamahi whakaahua ana te faaineineraa o tona mahi) he tika ki te whakapiki ake i roto i tona kaha osmotic. He nohoanga rite ki te hua o tenei tukanga riro atu whakaemi, me te wai, me ai puta te tauturu.

I tua atu ki te wāhine, faarahi lactulose hoki te secretion o ate, whakaongaonga te ate, me whakahaere nga tohu ate o te haurangi. I muri i tona tono tino whakaiti te nui o toto matū paitini, ngā haukini. Tikanga, kua whāpāharehia ratou e te pūtau ate - hepatocytes. Heoi, i roto i te tūroro ki te iti hoki ate, e tupu, mo te tauira, ate cirrhosis, e whenumi metabolites paitini i te whēkau, me te whai i te pānga paitini i runga i te roro. Ka rite ki te hua, whanake te manawanui ma'i encephalopathy tomokanga nahanaha (PSE) - he syndrome neuro-ira matatini. Kei te āhuatanga i te reira e disorders uauaio, disorders o whanonga me te mahara. Lactulose (kaiwhakamahi i runga i te whakahaere tarukino tohu tenei) ko te tarukino whai hua tino, tuku ki te hiki huru o te manawanui i PSE: whakarato reira he whakawātea tere o te haukini i te tinana, me te ārai tona absorption ki te toto.

Ko te mahi o te lactulose i runga i nga microflora intestinal rite ki te pānga o te muka kai, ngā whakamahia ki te hamani kōroke. Kua whakaaturia Studies e rite ki te hua o tona tono i roto i te punuatuna tino whakanuia ana te maha o te lactobacilli whai wāhi i roto i te nakunaku o kai. I tua atu, kei te whakamahia te reira i roto i ngā momo ngāwari o mate intestinal: whakaiti i roto i te maha o huakita gut pathogenic - tetahi o nga hua o te tarukino "Lactulose". e te tikanga o te tono o te ā-ta e inhibits reira te tini o Salmonella me māngai o te koripi - Shigella. No te mea o enei āhuatanga, whakamahia lactulose te i roto i te maimoatanga o te dysbiosis.

Ki te rā, hua te ao e rave rahi tekau o teuteu i runga i te pūtake o te lactulose "Duphalac", "Normase", "Livolak", "Laktofiltrum", "Laktusan" me etahi atu. Lactulose, tohutohu hoki te whakamahi i whakaahua ana i roto i te taipitopito te pānga taha taea o te tarukino, ko te wāhine pai mō ngā tamariki taitamariki, nga wahine ruhiruhia, hapu me te lactating. mahi reira ata me ata, tata kahore meinga hūhi. I roto i te pānga taha taea - mamae puku, me te bloating. I te tahi taime whakapairuaki me te ruaki te tikanga e pā ana ki reira ki te ātete kai takitahi ki te tarukino. I roto i tenei take, he mea e tika ana ki te mutu fariiraa.

Ko te akoranga o te maimoatanga ki lactulose ko, i toharite, hoki e pā ana ki e rua nga marama. Hoki te maimoatanga o te kōroke lactulose (kaiwhakamahi tika tohu te inenga tūtohutia) Kei te tuatahi tono i 15-45 ml ia ra (horopeta whakaritea takitahi). haere te torutoru ra ki te horopeta tiaki - ka waiho i te reira ahua iti. Ngā pēpi tirikara o lactulose e tūtohu ana (ngā kaiwhakamahi ki reira) ki te farii i te horopeta o 5 ml ia ra. A, no te te PSE i te timatanga o te therapy, memeha te reira i roto i te wai, me te te whakahaerea rectally 3-4 wā ia ra. I muri stabilization o te manawanui tangohia te tarukino te waha i te horopeta whakaritea e te rata.