Metastases Bone.

Ko tētahi o nga raruraru nui o te mate pukupuku katoa - te tīmatanga mooni o te atamira whakamutunga - i te wā o te metastasis. Metastasis aronga Ko neoplasms mārere e kua oti te tuhituhi te rere o te waitinana toto ranei i roto i whekau tawhiti me te kopa, ai haamata ki te whakawhanake i tukanga neoplastic.

Cancer o tata okana me te kopa katoa kia metastasize ki wheua. taea taua pāpaka e kitea i roto i tata tetahi hanganga wheua. Ko te tino auau - metastases i te tuarā, i te iti rawa i roto i te papatoiake, rara me wahi.

He aha te pukupuku metastasize ki te wheua?

Nuinga o ngā wā, puta tenei tukanga ka te thyroid repe mate pukupuku, repeure me te mammary repe.

E rua ngā momo taketake o te tukanga pathological i roto i te wheua - osteoblastic me osteolytic metatstazirovanie. Ko angamaheni hoki te puka tuatahi hiri o wheua kikokiko, i roto i ngā tona wähanga kohuke. tauturu te puka tuarua "horoi i roto i" o kohuke, e te taniwha, tura'ii te thinning me piere.

Ko te pathogenesis o tenei mate ko e e whakaihiihi pūtau puku. Ki te te metastasis o pukupuku tā osteoblasts i roto i te tukanga - puka osteoblastic whakawhanake. A, no te tutaki i te puku tuatahi i roto i to ratou ara i te wheua resorbing pūtau (osteoclasts) - ko te hanganga o metastases osteolysis.

I roto i te nuinga o te wā, te ahua o metastases i roto i te wheua ai mamae whakamutunga. meinga mamae syndrome e kino ki te kūmuri io growths puku, te hua pēhanga i roto i te wheua, a e tika ana ki mutunga ritenga o muka karere tohaina matū metastasis. I tua atu, puta te mamae, ka piere wheua meinga e thinning o te whakamutunga (āhuatanga o ngā osteolytic). Ki te hanga i osteoblastic hypercalcemia whakahuatia āhuatanga (konupūmā toto tiketike).

Ko te ati o piere ko te tūponotanga tiketike o pōauautanga - Embolism pūkahukahu, thromboembolism rua hohonu (te mutunga, arata'i tenei ki te mate o te mahi utanga okana alangá ranei me te kaha).

E pāngia metastases wheua te whakamahi i X-ray. Hoki tenei whakaaro, te whakamahi i Radiography mania i te liunga o pāpaka metastatic, me te puka osteolytic. I roto i te take o te osteoblastic kawea scans radionuclide. Ko tētahi o nga tikanga o te tuakiri, i e taea te kite kore metastases wheua anake, engari ano hoki i roto i te tahi atu whekau me te kopa - PET 18P-deoxyglucose.

whakaaturia maimoatanga hāparapara o metastases wheua te i te whatinga taea whakamutunga. whakamana taote orthopedic pokanga ki te whakapakari i te wheua mā te whakauru titi, me whakakiia te kau ki te wheua sima puku.

therapy radiation i te horopeta o e pā ana ki tekau ma rima - e rua tekau-rima GY (attributable ki te hautau whā), hawhe o nga tūroro ko te ngaro o te mamae. Ko te horopeta o toru tekau - e wha tekau-rima GY ai te whakapai ake nui i roto i te huru o te manawanui, i roto i ngā whakapainga i taua whakawhanakehia runga te puaretanga muri mō te rua - e toru wiki.

Ko te mahi tuarua i muri i radiation therapy, ko te whakamahi o te strontium iraruke. inaianei whānui kua whakamahia te reira i maimoatanga bisphosphonate. Tenei waikawa motuhake e tautāwhi i te mahi o osteoclasts. I tua atu, i tuku enei taero te pakeke o te mamae i roto i te piere o wheua, me te e te whanaketanga o te pukupuku.

Ko te kupu, ko te waitohunga hoki metastasis ki wheua kia rerekē, i runga i te localization o osteblastnoy osteolytic ranei puka me tikanga o te maimoatanga rānei.