Intranasal - Ko te whakahaere tarukino? formulations intranasal

He maha ngā huarahi rerekē o te whakauru i te tarukino ki te tinana tangata. I te ata o te rongoā tuatahi i whakamahia ngā tikanga rohe i roto i te puka o tono, rastirok, e kokopi, a-waha, tae atu i te ingestion o te maha o ngā puka inenga absorption sublingual ranei. Kua atu tikanga matatini whakamahia ki te whanaketanga o te hangarau hauora me te tuku o te taonga kaha ki te okana ūnga.

He nga suppositories rectal me tara (pire tou), papa multicomponent me capsules, tae atu ki ngā papa Uwhi, rewa pekitīlia ranei wai ranei whākōkī intestinal. tikanga i werohia: te pütahitanga, me te subcutaneous, intramuscular, rō-uaua, me te kōtuitui-matua, intraosseous. Kei te patia te tarukino ki te kōhao tahi, i nga okana.

Ahakoa te ara āhua ohie o whakahaere, endotracheal me intranasal formulations kua whakamahia ngā tata. O te akoranga, kua vai kua nga pata ihu i Hipokeletisí. Heoi, intranasal - ko tenei kotahi ara o whakahaere mō te tuku ki ētahi atu whēkau, ka ko e kore he rongoa mo huamo i te matao, ka kua taua whakahaere kua whakamahia he torutoru noa tekau tau ki muri.

Groups intranasal formulations, whakarato whānui (nahanaha) mahi

Kua whakakitea rangahau maha e te whawhai ki te matao noa - e kore te mea anake te take mo te whakataki o te tarukino ki te kōhao nasal. ata riro te maha o raau taero e whai he mahi pūnahanaha, i te membrane mucous o nga whitinga nasal, me te tae tika ratou ūnga.

Ko taea whakahaere Intranasal hoki:

• H1-antihistamines (pāwera);
• he-adrenoceptor agonists (vasoconstrictors);
• rewa stabilizers pūtau kiriuhi;
• serotoninergic (whakarato ngā pānga - o vasoconstriction ki te antiallergic);
• hormonal me protivogormonalnyh;
• Pë whakapōauau ;
• immunomodulators;
• correctors pākia o wheua ngohe me te wheua kiko;
• psychostimulants me nootropics.

whakahaere Rawa intranasal o taero

Kua tamata Tino he wa roa kamupene rongoā ki te whakaoti e rua ngā mahi unsolvable ki te faatura ki te whakamahi o te raau taero he te hanganga matū o te pūmua. Ko te tutukitanga waewae i te rangirua o te wae pūmua-peptide, he whakauru kaha i te wai pekitīlia me whākōkī intestinal i roto i te fariiraa-waha. Ano, kua meinga te raruraru te āhuatanga o te irava matamua i roto i te ate - mahi here o te matatini me tona excretion.

kitea te otinga i roto i te whakamahi o te ara injectable o whakahaere me suppositories rectal. Heoi, he rerekē ki etahi matatini hangarau te ara tuatahi, ngā ki sensations kino. A kihai i whai hua nui te tuarua no o absorbability iti i roto i te wāhanga whakamutunga o te tōu. haere mai ohorere te whakatau. I kitea te reira i taua intranasal - reira rite werohia, taua whakahaere, i nei te tīmatanga tere o te pānga haumanu. A, te tāpiri etahi matū whai pānga whakaratohia te pērā i bioavailability tiketike, i.e. te kukū hiahiatia o whakauru kaha i te pae o tona tono.

whakakitea tetahi whai hua rawa whakahaere intranasal i wahopūtau (bypassing absorption ki te bloodstream i roto i te mucous) kătahi o matū kaha ki te roro. Whiwhi i runga i te rohe olfactory, kua tukua te tarukino ki te muka o te olfactory me raru ko trigeminal.

Release hanga formulations intranasal

Hoki whakaurunga ki te kōhao nasal whakamahia te rawa he maha iti o puka rongoā. Ko te tuatahi ko te, o te akoranga, te ihu makaka. Mahalo puehu inhalation ki te hanganga pai. Whakamahia whakapanga hinu. e kore e tika ana ki te rongo poto ki te mucosa Various rongoā decoctions o otaota mō te horoi kōwhao nasal i roto i tenei rōpū ranei ka tono.

Ko te puka matua o te tuku taero intranasal he pānga pūnahanaha he Tāhorongia nasal. E hua ratou i roto i te puka o te dosing canisters ki te hau kōpeke ranei ki te kaha papu-atomizer. Ngā mihi ki te tetahi rōrahi o te pira rehu ka aki kotahi, he reira taea ki te inenga āhua controllable o te tarukino.

Ano, ka whakamahi i te rehu he whakanoho iho irrigation nasal mucosa. whakarei ake ana tēnei i te absorption o te tarukino e whakarei tona mahi pharmacological.

painga matua o te whakahaere nasal

I runga i te ake nei, he mea ka taea ki te tautuhi i te mau viretu matua nohoia e te formulations intranasal. Te noho noa me te tapatahi o te whakahaere, e kore nei e rapua e atu taputapu hangarau, me te whakangungu motuhake, i te mea he te take ki ngā tikanga werohanga e tino nui i to ratou whakamahi i te manawanui.

Ki te whaiaroaro, me te Pūtaiao o tūranga i runga i te wahi tuatahi ko te taea o te mahi pokapū i runga i te hanganga roro. Whakahuatia pānga pūnahanaha, haere mai i roto i te wa poto, rite i roto i te tikanga i werohia o whakahaere, he nui ano hoki te reira. Nā ki te ngaro o te tītohunga o te irava matamua i roto i te ate, whakarato bioavailability tiketike o te tarukino me te nui iti o e pā ana tauhohe kino.

Ko te āhuatanga

Mai i te tirohanga o te pānga pūnahanaha raruraru matua, ko te ki te mau tonu i te taumata whakaora i roto i te kukū toto wē o tarukino. Founga o tere whenumi me tae te tihi o te mahi mo te wa poto, kia taea anake te whakamahi i te whakahaere intranasal mō te ako o ngā āhuatanga wā-poto. Ko taea anake pānga auroa ka whakahaere taero e whai pānga i runga i te hanganga roro.

I tua atu, i te whanaketanga ka taea o tauhohe rohe ki te mucosa nasal. Ko te tika ki te kukū ka makona ratou tiketike o te whakauru kaha i roto i te hanganga o te ringihia, me te ihirangi o ngā wāhanga atu tenei ki te whakarite irava mōrahi o tarukino i te mata o te mucosa ki te toto.

kua ka hiahiatia āhei absorption i te kōhao nasal he maha tika whāiti o taero mo tenei āhuatanga physicochemical. Ko te manawanui ko te nui haere kukū o te whakauru kaha arata'i ki utu nui mo te hoko o te rehu.

immunomodulators intranasal

I roto i te atu-wa i roto i urutā maremare mo te ārai me te maimoatanga o te raau taero e whakamahia whānuitia e whakanui i te korero ārai whānui, me te rohe ranei.

Hoki te whakaaro o te ārai whawhati tata me te tiaki tono te interferon intranasal.

A, no te mea kua whakaaturia rangahau maha e te ara intranasal o whakahaere o immunomodulators whai wāhi kore anake ārai te kătahi o wheori, tukumate roto i te mucosa nasal. Reira whakaongaonga hoki te ope tiaki o ona ake - te faaitoitoraa o tona production ake o interferon. Hei whakaongaonga te hanga o endogenous therapy tiaki interferon rite te tikanga o te whakamahi i te tarukino "Anandina" intranasal.

interferon tangata

Ko te faaineineraa o motuhake mahi he tiaki ārai ki te nuinga o tukumate maremare viral, "Interferon" puta te i roto i te puka o papa, taka injectable me puehu mo te faaineineraa o pata. Hoki te ārai me te maimoatanga, ka taea e koe te whakamahi i tetahi ahua o te tuku. Ko mo tiaki rohe pai intranasally. Tenei, kia rite ki te arai e kitea e ārai kătahi o te nui o te huaketo i roto i nga pūtau o membrane mucous o te kōhao nasal. Tenei ka whakarato i tētahi pā raro i roto i ngā āhuatanga urutā.

Immunostimulant "Anandina", makaka kanohi me te nasal

Ko whānui whakamahia te tarukino tika ki te ngaro tata oti o ngā pānga taha, tauhohe kino, me te pai ngā pānga stimulatory ārai. I tua atu, kua hoki reira he taonga marutanga-whakaora korerotia e he nui i roto i tona tono rite makaka kanohi i te whara Corneal conjunctival ranei.

Contraindications kua anake homai intramuscularly "Anandina". whakaaetia pata nasal e i tetahi tau, hapū, hohipera me era atu tikanga whaiaroaro mate ranei.

Ki te Rhinitis pāwera

meinga pinepine ihu oranga, te tihe, me te kore secretion auau o te hūpē riro te huaketo, me te antigen, ārahi ki kore-motuhake ārai whakautu - mate pāwera. I roto i te maimoatanga matatini o tenei ahua o Rhinitis, kei te maha whakamahia corticosteroids intranasal. Ko rawa pono hoki te iwi e mate ana i ngā kaupeka o te mate pāwera tenei - tarutaru kirika.

I roto i etahi tipu wā pua taua tūroro he iti rawa anake tono taero antihistaminic rōpū, i roto i te nuinga o te wā whakaatu pānga atu me whakarokiroki. Ehara i te mea whakaaetia i raro i te whakahaere o waka nekeneke, mīhini whakahaere, i roto i ngā āhuatanga o te kukū hinengaro mōrahi ranei. Na ka whakaritea Tāhorongia hormonal rohe e tango faaiteraa o tohu, kahore nui pānga i runga i te whānui toenga hormonal.

mehua whakatūpato

Ahakoa te wātea whānui, me te ngāwari mateā o enei taero, he mea nui ki te mahara i taua intranasal - ko, rite tetahi atu, he tarukino e kia whakamahia anake i runga i whakahaunga o tākuta, i roto i te inenga whakaritea o ratou, liunga, me te roanga o te fariiraa.

E mea pinepine i reira he āhuatanga ina e hiahia ana koe ki te tango i te raau taero maha, te whakakorea e tetahi o e kore e taea e. Nō reira, ki te hiahia kitea i roto i ka whai ranei ratou ka ngā pānga kino i runga i te tinana. Tohutohu mō te whakamahi e taea ngā taatou katoa o mate pāwera. Ko te aha i mua i te tango i taua raau taero noa rite suppositories, hinu me Tāhorongia, kia tino kōrero koe he mātanga.