Rongoā paturopi "Linezolid": tohutohu mō te whakamahi, ritenga utu, te puka tuku, me arotake

Te nuinga o te rongoā mohiotia mate kitakita viral ranei Nireaha ki te maimoatanga e taero tikanga. Heoi, i reira he tukumate e kua taunga ki te tikanga nosocomial pera-ka karanga. Ko te whawhai ki a ratou ko te mahi tino uaua, no te mea he tokomaha taero ratou noa e kore e mahi. Rongoā paturopi "linezolid" e pā ana ki te hunga taero ki e taea te mahi ki pera-ka karanga mate nosocomial ranei atu ātete ki ētahi atu momo o taero. Ko te pā ana ki reira, a ka kia kōrero i roto i tenei tuhinga.

whakaahuatanga

tono Drug "Linezolid" tohutohu ki antimicrobial whanui-hihinga. E ai ki ona āhuatanga taketake me ngā āhuatanga no te reira ki te oxazolidinone piha haapiiraa e te kaha me te whānuitanga o te mahi ki microorganisms i roto i maha tikanga pai ki te tarukino "Vancomycin" me ētahi atu hua ki te hanganga rite.

I teie mahana, i reira e rave rahi momo o antimicrobial kaihoko "linezolid". puka Hua, kei te tino maha whakamahia i roto i te therapy, - papa he anga membrane kei roto 400 600 ranei mg o taonga kaha. I tua atu, i roto i te mahi hauora te maha whakamahia otinga e whaowhia, i roto i ia ritamano kei 2 mg o taonga kaha, me te paura (granules) ki te whakarite i te whakatārewatanga, te kukū o te whakauru kaha i te mea 100 mg ia 5 ml o hua whakamutunga.

Tuhinga

Ka rite ki whakahuatia mua i roto i tenei tuhinga, taunaki te tarukino ā-"Linezolid" ako e whakamahi koe i te aroaro o mate meinga e te huakita ātete ki ētahi atu paturopi. Ēnei ngā e rua karamu-pai, me te karamu-kino microorganisms no ki te anaerobic momo takohe ranei e kua whakawhanakehia ātete (pūmautanga) ki methicillin, pūhui gikopeptidnym, rongoā paturopi me ētahi atu paturopi.

Ko te rārangi o mate mo e ngā he "linezolid" ako medicament:

• hōhipera whiwhi hapori kakā ranei;
• mate kiri;
• mate kiko ngohengohe;
• Ētahi atu mate meinga e paturopi-ātete Enterococcus.

Ka rite ki te tikanga, i mua i te whakamahi i tenei tarukino whakahaere rangahau ki te tautuhi i te ātete o tukumate ki ētahi atu raau taero. Ki te kitea kahore te, kawea maimoatanga i roto ki te awhina o te tahi atu raau taero antimicrobial.

contraindications

Ko te contraindication matua, me te tino nui ki te whakamahi o te rongoā paturopi 'Linezolid' tohutohu mō te whakamahi e pā ana ki hypersensitivity ki reira. e kore te tūtohu hoki te reira ki te whakamahi i te tarukino hoki maimoatanga o tūroro e tango atu raau taero i te rōpū o inhibitors Mao. I tua atu, e kore a reira tūtohutia hoki tenei kaihoko tahi me pōuritanga tricyclic me matū ahei ki te whakaara pēhanga toto (epinephrine, dopamine, me ētahi atu triptan).

contraindicated faaineineraa "linezolid" (papa, otinga e whaowhia me te slurry) kei roto i mate pērā i takawhita, hyperthyroidism, ranei seratoninovy syndrome carcinoid, feohromotsitoz. Me kitea te aroaro o enei contraindications i mua i te tīmatanga o te therapy te whakamahi i te tarukino.

Tikanga o te mahi o raau taero i roto i te tinana

Mahi "Linezolid" tarukino tika ki tona kaha ki te ārai i te tukanga translation o ngā hanganga pūmua i te pūtau o te huakita. Nā ki te tini o microorganisms mutu te me i reira he mate to ratou. whakaputaina Ātete ki te tarukino i roto i te nuinga o te huakita te tino āta.

I muri i ingestion o te tarukino whakauru kaha hanga te glycine metabolite hydroxyethyl. Ko te tohu o tona rōpū ki pūmua wē tutuki te 31% mahi. I roto i te taiwhanga kitea rangahau e te ô i te pūhui ki te kopa me okana katoa. Kei reira hoki te kaha ki te haere i roto i te ewe ki te kukune me uma waiu (kitea tenei taonga o te raau taero i roto i te kupu tohutohu o te tango i te raau taero e te wahine hapu, me te lactating).

Ko te hawhe-ora o te taonga kaha, me tona metabolite excreted he 4.5-5 haora. Ko excretion mā te pūnaha mimi (50% rite te metabolite me 35% tonu), ka i roto i te wahi kūnatu (kore iti iho i te 9%). puta Whakaotia excretion i roto i 8-12 haora i muri i te fariiraa i medicament.

Me pēhea te ki te tango "Linezolid"

tohu Tohunga i roto i roto i te nuinga o te wā e kore e taea e hanga takitahi te manawanui he whakatau i runga i te tikanga o te fariiraa "Linezolid" tarukino. Note, papa, rongoā me rare kahore e i whakaaro rite taka motuhake, me rite ki te ahua o te tarukino, kei roto i tenei wāhi kōrero tonu. Kei raro ko nga ngā matua e pā ana ki te inenga, me te roanga o te therapy.

fokotuu Medicine "Linezolid" ā-ako mā te whakamahi i te kaupapa e whai ake nei:

1. whakahaerea te otinga mō te whaowhia te pâmuhia 2 ngā wā i te ra. He horopeta kotahi o te taonga kaha 400-600 mg. Ko te roanga o te maimoatanga tei runga i te pakeke o te mate, me tona localization. Tikanga, te nuinga o mate titau te wā o te iti rawa 10 me kore ra ake ake i 14, a anake i roto i mate meinga e enterococci, pumau maimoatanga i 2 ki te 4 wiki.
2. tangohia faaineineraa "linezolid" (papa) Kei te rite 2 nga wa he ra i roto i te nui o 400 600 ranei mg ia fariiraa. Hoki tūroro 5 ki te 14 tau te pakeke, tatau te inenga i runga i te pūtake o te taimaha tinana, a ko 10 mg ia 1 kg o taimaha tinana, 2 nga wa i te ra. Ko te horopeta mōrahi ia ingestion (poutāpeta) e kore e nui 600 mg. whakaritea te roanga o te therapy e te taua tawhā i whakaaro ai i runga.
3. Granules, e hanga nei e o te whakaehunga, tono e te kaupapa i runga ake. tātaitanga inenga i te mea e tika ana ki te kawe i roto i rite ki te aratohu taua.

Mai whakaritea te tarukino "Linezolid" Kei anake e whakahaunga me te whakamahia anake i roto i te fare ma'i, e tata whakakorea he tuwhena rawa o tenei whare me te ahua o ngā pānga taha korerotia. Doctors i roto i o ratou arotake whakahuatia take o whakaeminga te taikaha i roto i te tinana o te taonga tarukino kaha, me ona metabolites tika ki disorders o nga whekau mimi me te ate. Kei te nuinga o te tino hohoro nekehia nga hopearaa o taua overdoses, kia rite ki te tukinotia te manawanui i raro i te te tirotiro tamau o tohunga.

taunekeneke tarukino

Mai tetahi o nga momo inenga o te tarukino "linezolid" Ko te tikanga mo te whakahaere rō-uaua, he mea nui e he tino hototahi ki te rongoā taketake i whakamahia i roto i te maimoatanga (5% otinga kūhuka, 0.9% otinga o te konutai pūhaumāota te tarukino me te otinga o Ringer).

kia utua ngā whakarongo ki te huru o te tūroro, e i roto i te tua ki "Linezolid" tango raau taero adrenergic. Ki te kore e taea te makanga oti o te whakamutunga, Me ki arotake ratou inenga rata.

"(E taea hoki te te aifaito rite i roto i te hanganga ki reira) Linezolid 'Ko tino hototahi ki te taero" Medicine Chlorpromazine "," Cotrimoxazole "" Diazepam "me" Phenytoin ". Ki te te manawanui i mua i te tono o te rongoā paturopi mea mau he tika te tikanga ki te paturu wā 3 ra i mua ki te maimoatanga "linezolid" faaineineraa.

Ara

Ka rite ki tūtohutanga atu i runga i te whakamahi o paturopi kei "Linezolid" ā-ako mōhiohio e pā ana ki te hapu wahine me tangata ki comorbidities ngā. I tua atu, e tohu ana ki te taea o ngā pānga taha. Ko nga mea tuatahi te tuatahi.

Ko te fariiraa "Linezolid" arotake tarukino o ngā tākuta korero e pā ana ki tūpato motuhake ka whakahaere ki nga wahine hapu, me te lactating. Ko e tika ana ki te meka i e kua ako iti rawa te pānga o te raau taero i runga i te kukune whakawhanake ranei te tamaiti fanau tenei. Ko te tikanga, maimoatanga kei me tona whakamahinga he tika anake, ki te te mōrea ki te kukune tino i raro i te painga e tūmanakohia ki te whaea.

He tākihi me te pakeke kore ate, e rapu ana hoki tono tupato o te raau taero, no te mea kei te excreted te nuinga metabolites i roto i enei whekau, me te haaputuputuraa o enei matū i roto i a ratou kia meinga ino o te manawanui.

pānga taha

I runga i nga hua o ngā kitenga haumanu, tauhohe houhou o te ngā whēkau me ngā pūnaha i te fariiraa paturopi "linezolid" tino maha pā te pūnaha io, me te kūnatu. Mō 10% o tūroro i roto i te maimoatanga i kitea whakapairuaki me pāhoahoa. He iti iti māharahara e pā ana ratou korere, whanoke, me candidiasis i roto i te mucosa-waha.

I tua atu, tohu nga tohunga i roto i taua pānga e hiahiatia o te tarukino rite neuropathy piringa, hukihuki, waimaero ataata (ki runga, ki tona mate katoa), thrombocytopenia, serotonin syndrome, angioedema me te ru anaphylactic. Nā ki te meka i whakamahia te raau e anake i roto i te taiao hōhipera, e karohia nunu'a maha nui.

puta Treatment tauhohe houhou i runga i te wahi o symptomatic me ngā pūnaha. Ko taea Tangohanga o te raau anake, ki te te pakeke o ngā pānga taha ko te raruraru nui atu i te mate e tukinotia whakaaro paturopi.

analogues Drug "Linezolid"

pea i te pātai e pā ana ki ranei te "Linezolid" analogues o te tarukino reira kaipānui. O te akoranga, te mākete ho'oraa ki te kahore tonu, te mea i te torutoru taero e te hunga rite ki enei hanganga antimicrobial. Enei taero pā ana Serb paturopi "Zeniks" Norwegian "zyvox" me Iseraela "Linezolid Teva". Ko te hanganga o te katoa o enei taero rite te taonga kaha matua ngā linezolid.

He reira nui ngā rerekētanga i waenganui i nga tikanga, me te faaineineraa "Linezolid" whakarārangitia i runga ake? Ko te utu o te raau taero - e te te rerekētanga matua. Ko te meka Ko e ia te hanganga ano, mahi enei raau taero i runga i te tinana tangata i roto i rite te taua: aro ki te taua microorganisms, meinga te pānga kino taua ko te taua contraindications. Ehara i nui ngā rerekē me ngā tikanga o te maimoatanga me te inenga.

Ka rite ki te tikanga, te atu te utu analogues kawemai "Linezolid" paturopi whakamahia i roto i te kaupapa e kore he reira i roto i drugstores tenei tarukino ngā. tupu tenei maha, no te mea o tona whakamahinga o te whānuitanga o tūroro ngā he tata e taea e tika ana ki te whakahaunga rongoā, me te overdo runga i te whata e kore e tetahi o te mekameka rongoā faatiti'aifarohia. Mai i tenei iti tono rōpū taero me, na reira, ki te whai wāhi i etahi wāhi hoko tona take katoa.

Ko te utu o te tarukino

Ko te medicaments o te rōpū oxazolidinone i te utu nui e tika ana ki te ariā multistep matatini o te taonga i roto i ngā taiwhanga rongoā. He aha te mea te "Linezolid" utu tarukino? Papa (ihirangi o te matua taonga kaha 600 mg, mōkihi o 10 nga wahi) i roto i mekameka rongoā e te iti rawa 18 mano. Ko te uara mōrahi o tenei puka inenga ko 20 mano moni ia 10 papa. Paku ngawari te Ko te tarukino i te horopeta o 400 mg. Ko tōna utu he e pā ana ki 17-18 mano moni mō te 10 papa.

Ko te otinga mō te whaowhia "Linezolid" ka taea e koe te hoko i te iti bit iti: mōkihi o 10 pākete o 100 ml ka utu 7.5-9 mano moni, 10 mōkihi o 300 ml ia - i roto i te 15,3-16,2 mano moni.

maha tahuri nga whakatakataka a te taua ingoa, e he nui iti, i roto i ki te waiho i te tapehatanga me, i pai, i kahore pānga i runga i te tinana o te manawanui. Otiia, i te roa i roto i te therapy mo te mate, e āwhina kia whakakahoretia o te 'Linezolid' paturopi iho ko te tino mōrearea. Ko te aha tūtohu tohunga ki te tiki i te rongoā anake i roto i te pharmacies ki te ingoa pai.

Comments e pā ana ki paturopi "Linezolid"

varavara taea puna rerekē kitea arotake e pā ana ki paturopi o tenei piha. E pā ana tēnei tino ki ngā mōhiohio e pā ana ki tona whakauru, whakaahuatia tūroro. Ko e tika ana ki te meka i he te nuinga o nga tūroro i roto i therapy i roto i te huru tino nui, a ka mahara i te kawe-whakamua katoa o ongo'i ratou ko tino uaua tenei.

Mātanga, i roto i te tahuri, pahono ki rongoā "Linezolid" tino pai. E ai ki a ratou, e taea ki te akakoromaki i ara nga iroriki tino ātete te tarukino ko. tohu hoki ratou i roto e te mōrea o pōauautanga tika ki ngā pānga taha tuwhena rawa ranei he tata oranga. Ko e tika ana ki te meka i whakamahia te rongoā paturopi te anake i roto i ngā tautuhinga hōhipera tenei. I te tohu tuatahi o te mate pāwera kino ranei ki te tarukino e kawea atu nga ngā tukanga hauora e tika ana katoa ki te whakakore ratou.

Na, ka titiro matou ki te kōrero katoa o te tarukino "linezolid". i whakaahuatia tohutohu mō te whakamahi, utu me ngā hohenga tarukino taea i roto i tenei pepa i roto i te taipitopito. Me kï reira e, ahakoa te utu tiketike o te raau taero, tona whakamahi he tika i roto i te take katoa. Hei whakatau i runga i te maimoatanga o te tūroro tenei tarukino taea rata anake.