Neuroblastoma i roto i ngā tamariki, 4 atamira. Take, tohu, tohu, waitohunga. maimoatanga neuroblastoma o te tamaiti

Neuroblastoma - he mate pukupuku o te pūnaha io pukuaroha. I roto i te nuinga o te wā, kitea tenei mate i roto i ngā tamariki taitamariki. Wā whakanuia ana tona rapunga i nga tūponotanga o te ora oti. Mai i te rauemi o tenei tuhinga ka ako koe i te take taketake o te mate, he aha tohumate e haere tahi ai, te wahi e hiahiatia maimoatanga te.

āhua Amazing o neuroblastoma i roto i te tamaiti

Neuroblastoma - te tino noa puku ko te mārere pūāhua. Pūkete reira hoki e pā ana ki 15% o te wā korerotia katoa o te pukupuku o te wā fā'ele'i me kōhungahunga. Tohunga tikanga heheu puku i roto i ngā tamariki ki runga, ki te rima tau e, engari i reira he take o te mate i roto i ngā taiohi 11 me tae noa 15 tau. Ki te tupu me te whanaketanga o te tamaiti pea ki te kanohi i tenei mate haavare e iti te katoa tau.

Huamo o te neuroblasts, rite ki tākuta, kua fakakoloa'i ai ki ngā pūmanawa mīharo. Ko reira tino pukuriri, me te pängia ana ki te metastasis i roto i tetahi wahi o te tinana. mamae te nuinga maha i tona mahi o te wheua, me te pūnaha lymphatic. aronga tupu neuroblast ētahi wā whakaritea tākuta ratou wehenga ki te hanganga muri o te pukupuku. Ia te tuatahi metastasizes, ka whakatārewa tona whanaketanga, me te tīmata ki te regress. Malignancies o tetahi atu momo e kore āhuatanga e taua tohu.

Brain neuroblastoma i roto i ngā tamariki i te tuatahi whakawakia e pūtaiao i Germany, Rudolfom Virhovym i 1865. Te tākuta i huaina puku "glioma." Tau matahiti i muri mai te pūtaiao American Dzheyms Rayt torotoro i atu neoplasm taipitopito a faataa i taipitopito te tukanga o tona hanganga.

Ko te wāhanga whanaketanga o neuroblastoma

Ka rite ki tetahi atu pukupuku mate pukupuku, neuroblastoma i roto i ngā tamariki haere i roto i te maha o ngā wāhanga o te whanaketanga o tikanga, rite tautuhi taea ki a koe tautapa he maimoatanga whai hua:

• Kaupae 1 āhuatanga e te aroaro o te pukupuku resectable nei te rahi e kore e nui ake 5 cm, me te ngaro o metastases waitinana kōpuku.
• 2A Hipanga. Taunakitanga o te pukupuku paetata, he te nuinga o nei i raro ki te tango.
• Hipanga 2B. Waitinana metastases kōpuku puta e tareka e.
• Hipanga 3. Āhuatanga e te ahua pukupuku më.
• Hipanga 4 (A-B). tupu Neoplasm, i reira he metastasis ki te wheua wheua, ate me te waitinana kōpuku.

Me whai whakaaro ano hoki tatou e founga te wā whakamutunga o te whakawhanake i neuroblastoma i roto i ngā tamariki. Hipanga 4 rerekē kore i rawe ki neoplasias āhuatanga koiora okioki, kua he waitohunga pai, a ki te homai maimoatanga wā he auau ora tiketike.

Ko te take matua o te whanaketanga puku

Neuroblastoma, me ētahi atu momo o te mate pukupuku, whanake i runga i te whakamārama o irakētanga ira i roto i te rauropi. I tēnei wā, e kore e taea e tohunga te mea e hoatu ana e ia ara ki enei huringa. Kei te riro te reira e te tūranga takaro e te āhuatanga carcinogenic pera-ka karanga, arā, matū me te radiation. timata nga pūtau irakētanga hua ki te proliferate, hanga he puku. neoplasm mārere āhuatanga e te kaha ki te faaite i taua titore reira i mārire.

Irakētanga o whakapataritari te hanganga o te neuroblastoma whakatika i roto i te wā o te whanaketanga fetal ranei hohoro i muri i whanau o te tamaiti. Na reira, te nuinga o tūroro - grudnichki. Ko te takenga mai o te puku tīmata i roto i neuroblasts. Tenei pūtau io teeki, e kua hanga e i roto i te kukune i roto i tona whanaketanga intrauterine. I roto i te akoranga noa o neuroblasts hapūtanga amo te mahi o muka karere pūtau ranei he kawenga mō te hanganga o te repe adrenal.

te nuinga o ratou i hanga e kua te wa o te whanautanga o te tamaiti. te tikanga ngaro ngā pūtau teeki. A, no te te tukanga pathological o neuroblasts i roto i tenei tahuri ki te puku. Ko te taunakitanga anake o te tauwehe pukupuku - he predisposition ira. Heoi, e kore e nui ake te mōrea o te mate tuku 2%.

Nuinga o ngā wā, tākuta tātari neuroblastoma retroperitoneal, he wāhi tino i reira localization - te repe adrenal. Takahi, kia ara ake i te puku ki hea i roto i te tinana. neuroblastoma Retroperitoneal i roto i ngā tamariki puta i roto i te 50% o te wā, 30% o tūroro whakawhanakehia nodules puku o karere te rohe lumbar, te toe 20% whiriwhiri mo te localization o waha, me te rei.

Nahea te puku?

I te wāhanga tuatahi o te tukanga pathological o tohu motuhake e kore e kitea. Na reira, ko te puku maha kitea hoki ētahi atu mate motuhake ki tenei rōpū pakeke.

Tohu o neuroblastoma i roto i ngā tamariki anoo i runga i te wahi o te pukupuku localization, ngā wāhanga o te horapa metastatic, me te taumata o ngā matū vasoactive. Nuinga, Ko te kōpuku puku tuatahi i roto i te wāhi retroperitoneal, atu ïa i roto i te repe adrenal. I roto i te wā onge, kua paetata reira i roto i te kaki ranei i roto i te mediastinum.

Nahea neuroblastoma i roto i ngā tamariki? E meinga e te tuku o hormones e ngā pūtau mate pukupuku puku pēhanga tamau i runga i tetahi i te tahi atu tinana ranei ranei Tohu o te mate. I te tahi taime pānga tona tupu te mahi o nga whekau, me te tōngāmimi. Nā ki te kōpeketanga o oko toto i roto i ngā tūroro puta Tunaroa me raro edema pito.

He tohu o te neuroblastoma i roto i ngā tamariki hoki wahi whero kikorangi ranei i runga i te kiri. Ratou ahua tohu whai wāhi i roto i te tukanga pathological o ngā pūtau epidermal. Ki te kătahi o te puku tika ki te hinu wheua wheua o te tamaiti riro ngoikore, maha mate. I roto i tenei take, ka taea e ara he patunga iti hua i roto i te toto whānui.

Fakatokanga'i nga tohu o neuroblastoma, kia mātua kōrero te tākuta. rapunga o mate pukupuku i te wā wawe e taea te whakaora ora o te tamaiti.

neuroblastoma Retroperitoneal

Neoplasm o takenga neurogenic o te kikokiko e puta i roto i te wāhi retroperitoneal, āhuatanga e tupu tere. I roto i te wa poto, te ô i reira ki te awa filosilivá, hanga he ōrite matotoru o te puku, e taea te kitea i te palpation.

Neuroblastoma o te repe adrenal i roto i ngā tamariki te tīmatanga e kore tohu motuhake tae noa ki tae te reira i te rahi faahiahia, me te tīmata ki te tāpiri kopa pātata. He aha e nga tohu o te puku kitea?

1. Ko te aroaro o te hanganga mātotoru i roto i te kōhao puku.
2. Huamo o te tinana katoa.
3. Hūhi me te mamae i roto i te rohe lumbar.
4. mate Taumaha.
5. He hua i roto i te pāmahana.
6. Huringa i roto i te tohu toto whakaatu ki anemia.
7. Te kōpā, pāpāngia o nga wahi o raro.
8. Tere i te aravihi mahi o te wahi gastrointestinal me te pūnaha mimi.

Ētahi atu localization o te pukupuku takenga neurogenic

tahi Neuroblastoma mediastinum posterior i roto i ngā tamariki e te mate taimaha koi, uaua horomia, he mate o te mahi romahā. I roto i ētahi wā, arata'i te mate ki te huringa i roto i te āhua o te pouaka.

He tino onge zaglazno wāhi pukupuku, ko ratou e mohio atu e pā ana ki a ratou. Ko tenei e tika ana ki te meka i nga tohu katoa o te tukanga pathological kitea ki te kanohi tahanga. Neoplasm āhuatanga e te ahua o te wahi pouri i runga i te kanohi, i titiro rite te pakaru tonu. tuku iho tētahi atu tohu te neuroblastoma kamo. hipokina te reira i te 'Afio i puwhenua te ngawha.

puka neuroblastomas

I tohunga reira wehewehe neuroblastoma wha puka, ia o nei he wahi tetahi, me te localization āhuatanga motuhake.

• Medulloblastoma. mea putake hohonu i roto i te roro tuarongo, i te mea he aha e kore ai e taea te nekehia atu e te pokanga Neoplasm. huru no te māuiuitanga e te metastasis tere. Ko te tohu tuatahi o te mate pukupuku puta incoordination.
• Retinoblastoma. Tenei puku repara e pā te etine o te kanohi i roto i ngā tūroro taitamariki. Ko te kore o te maimoatanga arata'i ki katoa matapo me te roro metastases.
• Neyrofibrosarkoma. paetata tēnei puku e i roto i te kōhao puku.
• Simpatoblastoma. Ko te mārere tenei puku, i te mea tana "whare" kōwhiria e te pūnaha io pukuaroha me repe adrenal. Neoplasm i hanga i roto i te kukune i roto i tona whanaketanga intrauterine. Nā ki te hua tere i roto i te ua kia pāngia i roto i simpatoblastomy rahi e tura'ii te pāpāngia.

Me pēhea te ki te ite i neuroblastoma?

I te tīmatanga, whakatakoto te tākuta he tātaritanga whakapae toto me te mimi whakamātautau 'Neuroblastoma'. I roto i te tamariki, e rite ki ētahi atu mate nga tohu o tenei mate, me te taiwhanga whakamātautau o ngā rauemi koiora faaore atu take ka taea. reiti High o hormones catecholamine i roto i te mimi tohu te aroaro o te mate pukupuku.

Hei whakatau i te rahi o te puku, whakaritea tona localization tūroro taitamariki CT, ultrasound me MRI. He tikanga nui he unuhanga tātaritanga. I roto i tenei tikanga, hanga he mātanga te pūtau taiepa mate pukupuku mō te whakamātautau taiwhanga muri, tātari histological.

I runga i nga hua whakamātautau whakawhanake te tākuta tātai o te maimoatanga, ārahi mō ngā mātauranga i te maimoatanga me te ara o te ora o te manawanui.

kōwhiringa therapy

Kei te nuinga o te wā whai wāhi maimoatanga o te neuroblastoma i roto i te tamaiti i roto i maha tari mātanga matepukupuku (himioterapevt, taote, radiologist). I muri ako nga āhuatanga o te puku, kei te whanake tākuta tātai o tona whakangaromanga. Tei te reira i runga i te āhua o tali te puku ki te mahi kawea i roto i, me te matapae i te wa o te tātaritanga whakamutunga.

Ko te tikanga, maimoatanga o neuroblastoma i roto i ngā tamariki ngā te tikanga e whai ake nei:

1. Hahau. Tenei tukanga tā te whakataki o taero anti-mate pukupuku i te kaupapa i āta hangaia. Teuteu pānga te waipiro i runga i te pūtau mate pukupuku, te ārai ratou uri. Ki te ratou uesia atu wahi o te tinana, e arata'i ki te pānga taha noa (huruhuru mate, whakapairuaki, korere). nui haere te tōtika o te therapy e rave rahi taime i roto i te taha ki te transplantation o wheua.
2. maimoatanga hāparapara Ko tā te tango o te pukupuku. I mua i te mahi tono te hahau. āhei te reira ki a koutou pōturi iho tupu puku, me te take inenga o metastases. Admissibility whakaoti tei tona tango i runga i te wāhi me te rahi. He puku iti kei tata te ua, te wawaotanga rawa meá.
3. Radiation therapy i roto i te mahi hauora hou te uaua whakamahia. Ko piki te reira i roto i nga tau tata nei whakakapi rite te pai pokanga rite radiation kore he haumaru, me te waha ana i te tetahi riri ki te ora o te tamaiti. tūtohutia radiation therapy te tino i runga i te taunakitanga, ka reira te mea he tōtika iti o te tahi atu tikanga o te maimoatanga, i roto i te take o te neuroblastoma unresectable i roto i ngā tamariki.

e kore te te kai motuhake ki te tātaritanga tūroro iti tohua. Kei te ngana tokomaha ngā mātua ki te mahi ki katoa o huarahi o te ora o Chad, whakarite i tona kai. Kei te whakamatauria te reira e etahi o nga hua ranei, atu ïa, i roto i te matū i roto i a ratou, whakanui i parepare o te tinana, me te mārika i tautāwhi i te tupu o te pukupuku. Taua matū ngā konutea, rino, betaine, ngā huaora. He taonga i roto i te hua citrus, greens taitamariki, kāreti, te paukena ratou.

Ko te angitu o tetahi maimoatanga, tei runga i neuroblastoma pehea nui i roto i ngā tamariki. He nui hoki nga take o te mate, me te wā o te mate. Te whakamahi tikanga tuwhena i roto i te tīmatanga o te puku hanganga homai tumanako mo te ora tonu. Heoi, e kore e tenei atawhai te manawanui iti i runga i haere ki te tākuta, me te haere i te whakamātautau i roto i te tikanga ki te ārai i te hohokitanga taea.

e kore te tūponotanga whakaora whakamutunga waho i roto i te taahiraa tuarua, whakaratohia e te mahi angitu me te hahau.

whakatika atu etahi fifi i roto i te wāhanga whakamutunga o tenei māuiuitanga rite neuroblastoma. Tamariki 4 wāhanga o te mate pukupuku kei te nuinga o te wā tahi e te matapae matekiri. Ko taea matahoki i muri i tango o te puku, i runga i te whakamārama o huru ora. Ko te whakatupuranga i muri o te natura mārere te nuinga o te wā i hanga i roto i te wahi taua wahi i reira i mua. Ko te matapae mō tenei taahiraa ko 20% ora mo te rima tau. I roto i tenei take, tei mea katoa i runga i te whakangungu o ngā mātanga, te wātea o te taputapu e tika ana hauora.

outlook

I muri kaha waitohunga therapy matepukupuku hoki te nuinga o ngā tūroro he pai. Tamariki ki te tukanga puku paetata, mea pea ki te ora i rite wawe tonu tākuta. Ki te whakaaro ki tenei kāwai o tūroro, kia ngaro te puku noa kahore pokanga, engari kaha therapy hauora i roto i tenei take he whakahauanga. I roto i ngā tamariki pakeke, ka horahia atu te puku, he nui raro nga tūponotanga o te ora oti. Ano, Ka taea e te puku auau.

Ko te putanga o te maimoatanga maha whai he neuroblastoma tuarua i roto i ngā tamariki. Matapae i roto i tenei take e kore ko te pai tino. kia puta ano te puku i muri i te tau torutoru, tae atu i muri i te maimoatanga angitu. Tenei ahua o pānga i roto i te rongoa tuku ki ngā pānga taha rite te mutunga. Ko te aha tūroro katoa kaore he aweretanga, i muri i te akoranga o te therapy e tūtohu e tākuta te kitea tonu.

āraihia

e kore e Doctors hoatu tetahi tūtohutanga motuhake mō te ārai i te whanaketanga o te āhua mārere o te puku me te te take mo tona hanganga e tonu i matau ruarua, ki te haunga o te predisposition tuku mahara. Ki te ake i whanaunga tata ki te mahi ki tenei haavare e pāngia i roto i te whakamahere hapūtanga he minaminatia ki te haere i te kōrero o te geneticist doctor-. Ko reira pea ki te āwhina i te karo raruraru heke mai e pā ana ki te whanau o te tamaiti hawata ana.

Kia aroha mai, Kei te inaianei piki pāngia pukupuku i roto i tūroro taitamariki he kahore neuroblastoma okotahi i roto i ngā tamariki. Ka taea te kitea māuiuitanga Photo i roto i motuhake pukapuka tohutoro hauora. Ko te tikanga motuhake o te ārai, e kore e taea e ngā tākuta whakahere no te mea o te māuiuitanga etiology mārama. A, no te he ngaahi nga tohu tuatahi o tenei mate, ko te mea nui ki te rapu i tohutohu hauora. Anake i muri i te haere i roto i te aro mātai tātaritanga oti taea whakawa te huru o te pukupuku, me te ki te whakawhanake i te rautaki maimoatanga hi'oraa maitai. Ka whakau te tohunga mua te tātaritanga whakamutunga, te pai te tūponotanga mō te ora tonu. E noho hauora!