Nui haere PTH - rite kitea e te tātari?

taiki Parathyroid (te kore i huaina taiaki parathyroid, parathyrin) - he taiaki whakaputaina e te kiko (parathyroid) repe parathyroid, e kua kei i te taha anterolateral o te kaki. Ko ratou i muri i te repe thyroid, i te mea tata tata ki te mata muri o reira me te wahi o raro o tona hea e rua. taiki Parathyroid i roto i to ratou natura matū ko te taonga pūmua matatini - polypeptide amino pärönaki waikawa.

Ko tōna mahi matua, ko te ki te whai wāhi me te ture o te konupūmā me te ūkuikui pākia i roto i te tinana. Ko te ihirangi o te konupūmā i roto i te toto me te secretion o taiaki parathyroid e tika ti'aturi i ia atu. Ka taea e te taiaki ake i te kukū konupūmā mā te mahi i runga i te wheua kikokiko, tākihi me te wahi gastrointestinal. faarahi te parathyrin wheua takiputa tātau te wahi kohuke i whakaongaonga ariā o whākōkī motuhake e he kawenga mō te rärangi o te rauemi wheua. i raro wheua kiko te i raro i te mana o PTH resorption me te konupūmā ngā katote e kei roto i te toto. Fakataha ki te konupūmā utu paratgormot āwhina ki te whakahaere i te taumata o te Phosphate i te tinana. Whakaiti i te kaha o te tukanga koiora tuatahi, ee faarahi ho'ii te reira te rua o nga rere. Ano, whai wāhi te taiki e i roto i te whakarei ake ariā o calcitriol i te whēkau, te āwhina konupūmā reabsorption. taiaki Parathyroid e he wahi autaki i roto i te ture o nga mahi o whākōkī konupūmā-ti'aturi katoa katalirizuemye ratou tauhohenga. I raro i tona mana whiwhi hoki te pūnaha toto coagulation.

Ki te teitei PTH te, ka hanga e nui mate endocrine e pā ana ki te wheua tapatahi ofatiraa - hyperparathyroidism, me osteoporosis. Ko te hua o taua koha whaiaroaro koi heke i roto i ngā taumata konupūmā toto, e tika ana ki te nui haere excitability uauaio. Comorbidities i roto i tenei take e taea te mahi ihirangi alkali tiketike i roto i te tinana, me te whanaketanga o te täkihi. Na roto i te whakaiti i te ihirangi o te konupūmā i roto i te arotahi kanohi pokonga puta.

Taumata o te taiaki o te repe parathyroid i roto i te toto he kaupapa ki te manawataki circadian. whakaturia te taumata basal te i pā ana ki 8 am, i roto i nga haora 14-16 o te ra, ka ko te tangata i te tihi o te mahi, nui haere ira parathyroid. kawea whakamātautau toto i roto i te maha o te parathyrin immunohemilyuminestsentsii. Me hanga e te reira i te puku kau, ki te ra i ranei e rua i mua i tīpako toto faaore waipiro horomanga me mahi taimaha mō te hāora i mua i te tukanga, e kore e paowa.

I te tātari o te taiaki parathyroid whakaritea te anake ka whakapae te manawanui ko te oraraa o mate pērā i hyper- me gipokaltsimiya, urolithiasis me neurofibromatosis. Hoki kia ngā tohu mō te tātari whakaaro: wheua roa osteoporosis psevdoperelomy, tetahi whaiaroaro taui osteosclerosis wheua ranei tinana vertebral me whakapae endocrine maha momo neoplasia 1 me te momo 2 (MEN 1.2). I te auau parathormone mo te pakeke whakaaro te 9,5-75 wh / ml. E pā ana tēnei ki e rua tangata, me nga wahine o tau uri. Ki te kitea e hakeaki'i te PTH te, i reira he take katoa ki te amo i taua te manawanui he tuatahi, tuarua, hyperparathyroidism wānanga, pseudohypoparathyreosis Zollinger-Ellison syndrome ranei.

I raro i te hyperplasia hyperparathyroidism tuatahi ngā o te repe parathyroid, mate pukupuku o te kiko repeure me te endocrine neoplasia rua momo. Co. hyperparathyroidism Tuarua ngā iti hoki ma'i tākihi, hypervitaminosis D, colitis ulcerative, kōiwi, mate a Crohn. Ki te teitei PTH te, ka te nuinga o mahi te tātari i roto i te taha ki te whakamāramatanga o te taumata o te konupūmā i roto i te toto me te i roto i te heke mai te whakarite o rua tohu, me te tāutu i ririki.